iPTMnet Report for Q9UPQ3 (AGAP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UPQ3 / AGAP1_HUMAN
Protein Name Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1
Gene Name Name: AGAP1
Synonyms:CENTG2,KIAA1099;
Organism Homo sapiens (Human)

PRO ID PR:Q9UPQ3
DAG View
PRO Name Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (human)
Definition An Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 that is encoded in the genome of human.
Short Label hAGAP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UPQ3 (AGAP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
Y3 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
T232 Phosphorylation PhosphoSitePlus
T303 Phosphorylation PhosphoSitePlus
T305 Phosphorylation PhosphoSitePlus
S311 Phosphorylation PhosphoSitePlus
S315 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S320 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
Y369 Phosphorylation PhosphoSitePlus
Y380 Phosphorylation PhosphoSitePlus
Y387 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
S421 Phosphorylation PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S534 Phosphorylation PhosphoSitePlus
T604 Phosphorylation PhosphoSitePlus
S605 Phosphorylation PhosphoSitePlus   UniProt 23186163
S663 Phosphorylation PhosphoSitePlus
T836 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
S840 Phosphorylation PhosphoSitePlus
S849 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S315 Phosphorylation HPRD 18669648
T836 Phosphorylation HPRD 19664994, 19664995
Site PTM Type PTM Enzyme Score Source PMID
S315 Phosphorylation HPRD 18669648
S452 Phosphorylation PhosphoSitePlus
S454 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
T783 Phosphorylation HPRD 19664994, 19664995


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y3 F3 Biomuta DOID:1324 / lung cancer [ cosmic ]
T303 M303 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S315 F315 Biomuta DOID:4159 / skin cancer [ cosmic ]
S315 Y315 Biomuta DOID:1324 / lung cancer [ cosmic ]
S320 P320 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
S452 G452 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S521 P521 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S534 T534 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
T604 M604 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]