Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UPP2 / IQEC3_HUMAN
Protein Name IQ motif and SEC7 domain-containing protein 3
Gene Name Name: IQSEC3
Synonyms:KIAA1110;
Organism Homo sapiens (Human)

PRO ID PR:Q9UPP2
DAG View
PRO Name IQ motif and SEC7 domain-containing protein 3 (human)
Definition An IQ motif and SEC7 domain-containing protein 3 that is encoded in the genome of human.
Short Label hIQSEC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UPP2 (IQSEC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S47 Phosphorylation PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
K177 Acetylation PhosphoSitePlus
C282 Methylation IEDB 31844290
Y309 Phosphorylation PhosphoSitePlus
Y329 Phosphorylation PhosphoSitePlus
T360 Phosphorylation PhosphoSitePlus
S618 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S173 F173 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K177 E177 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y309 * Biomuta DOID:363 / uterine cancer [ cosmic ]
Y309 H309 Biomuta DOID:1319 / brain cancer [ cosmic ]
T360 P360 Biomuta DOID:184 / bone cancer [ cosmic ]