iPTMnet Report Q9UPN6 SCAF8

Protein Information

UniProt AC / UniProt ID	Q9UPN6 / SCAF8_HUMAN
Protein Name	SR-related and CTD-associated factor 8
Gene Name	Name: SCAF8 Synonyms:CCAP7;
Organism	Homo sapiens (Human)

PRO ID	PR:Q9UPN6 DAG View
PRO Name	SR-related and CTD-associated factor 8 (human)
Definition	An SR-related and CTD-associated factor 8 that is encoded in the genome of human.
Short Label	hSCAF8
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9UPN6 (SCAF8) as Substrate

Expanded View

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position T6 Y12 Y17 K18 S22 K31 K53 K81 S89 T95 K119 K124 S273 K281 S443 S445 S447 K461 S536 K542 S605 K609 T611 T614 T615 S617 T619 S686 S779 S780 T807 S821 S822 S824 S861 R917 R927 R938 R967 R981 R988 R1062 R1073 K1091 R1120 R1122 R1124 R1129 R1133 R1139 Y1198 Y1237	PTM Type Select all Acetylation Methylation O-Glycosylation Phosphorylation Sumoylation Ubiquitination	Score Select all 1 2 3	Source Select all GlyGen PhosphoSitePlus UniProt phospho.ELM	PMID
T6	Phosphorylation	score3	PhosphoSitePlus UniProt	20388717
Y12	Phosphorylation	score1	PhosphoSitePlus
Y17	Phosphorylation	score1	PhosphoSitePlus
K18	Sumoylation	score1	PhosphoSitePlus
K18	Ubiquitination	score1	PhosphoSitePlus
S22	Phosphorylation	score1	PhosphoSitePlus
K31	Ubiquitination	score1	PhosphoSitePlus
K53	Ubiquitination	score1	PhosphoSitePlus
K81	Ubiquitination	score1	PhosphoSitePlus
S89	O-Glycosylation	score1	GlyGen	23301498, 20068230, 33214551, ...28510447, 35138101, 34019948, 30379171, 34725712, 27114449, 29351928, 35132862, 22661428, 31492838, 35254053, 35289036, 30620550, 28657654, 30059200
T95	O-Glycosylation	score1	GlyGen	23301498, 20068230, 33214551, ...28510447, 35138101, 34019948, 30379171, 34725712, 27114449, 29351928, 35132862, 22661428, 31492838, 35254053, 35289036, 30620550, 28657654, 30059200
K119	Ubiquitination	score1	PhosphoSitePlus
K124	Ubiquitination	score1	PhosphoSitePlus
S273	Phosphorylation	score2	PhosphoSitePlus UniProt	23186163
K281	Ubiquitination	score1	PhosphoSitePlus
S443	Phosphorylation	score1	PhosphoSitePlus
S445	Phosphorylation	score1	PhosphoSitePlus
S447	Phosphorylation	score1	PhosphoSitePlus
K461	Acetylation	score1	PhosphoSitePlus
S536	Phosphorylation	score1	PhosphoSitePlus
K542	Ubiquitination	score1	PhosphoSitePlus
S605	O-Glycosylation	score1	GlyGen	23301498, 20068230, 33214551, ...28510447, 35138101, 34019948, 30379171, 34725712, 27114449, 29351928, 35132862, 22661428, 31492838, 35254053, 35289036, 30620550, 28657654, 30059200
K609	Acetylation	score1	PhosphoSitePlus
T611	O-Glycosylation	score1	GlyGen	23301498, 34846842, 33214551, ...28510447, 35138101, 34019948, 30379171, 34725712, 27114449, 29351928, 35132862, 22661428, 31492838, 35254053, 20068230, 35289036, 30620550, 28657654, 30059200
T611	Phosphorylation	score1	PhosphoSitePlus
T614	O-Glycosylation	score2	GlyGen PhosphoSitePlus	23301498, 33214551, 32938750, ...35138101, 34019948, 30379171, 34725712, 28510447, 27114449, 29351928, 35132862, 22661428, 31492838, 35254053, 20068230, 35289036, 30620550, 28657654, 30059200
T615	O-Glycosylation	score2	GlyGen PhosphoSitePlus	23301498, 33214551, 28510447, ...35138101, 34019948, 34846842, 30379171, 34725712, 27114449, 29351928, 35132862, 22661428, 31492838, 35254053, 20068230, 35289036, 30620550, 28657654, 30059200
T615	Phosphorylation	score2	phospho.ELM PhosphoSitePlus UniProt	17525332
S617	O-Glycosylation	score1	GlyGen	23301498, 20068230, 33214551, ...28510447, 35138101, 34019948, 30379171, 34725712, 27114449, 29351928, 35132862, 22661428, 31492838, 35254053, 35289036, 30620550, 28657654, 30059200
S617	Phosphorylation	score2	phospho.ELM PhosphoSitePlus UniProt	17525332, 23186163, 15302935, ...21406692, 18669648
T619	Phosphorylation	score1	PhosphoSitePlus
S686	O-Glycosylation	score1	GlyGen	23301498, 20068230, 33214551, ...28510447, 35138101, 34019948, 30379171, 34725712, 27114449, 29351928, 35132862, 22661428, 31492838, 35254053, 35289036, 30620550, 28657654, 30059200
S779	O-Glycosylation	score1	GlyGen	23301498, 20068230, 33214551, ...28510447, 35138101, 34019948, 30379171, 34725712, 27114449, 29351928, 35132862, 22661428, 31492838, 35254053, 35289036, 30620550, 28657654, 30059200
S779	Phosphorylation	score2	PhosphoSitePlus UniProt	23186163
S780	Phosphorylation	score1	PhosphoSitePlus
T807	O-Glycosylation	score1	GlyGen	23301498, 20068230, 33214551, ...28510447, 35138101, 34019948, 30379171, 34725712, 27114449, 29351928, 35132862, 22661428, 31492838, 35254053, 35289036, 30620550, 28657654, 30059200
S821	O-Glycosylation	score1	GlyGen	23301498, 20068230, 33214551, ...28510447, 35138101, 34019948, 30379171, 34725712, 27114449, 29351928, 35132862, 22661428, 31492838, 35254053, 35289036, 30620550, 28657654, 30059200
S822	O-Glycosylation	score1	GlyGen	23301498, 20068230, 33214551, ...28510447, 35138101, 34019948, 30379171, 34725712, 27114449, 29351928, 35132862, 22661428, 31492838, 35254053, 35289036, 30620550, 28657654, 30059200
S824	O-Glycosylation	score1	GlyGen	23301498, 20068230, 33214551, ...28510447, 35138101, 34019948, 30379171, 34725712, 27114449, 29351928, 35132862, 22661428, 31492838, 35254053, 35289036, 30620550, 28657654, 30059200
S861	O-Glycosylation	score1	GlyGen	23301498, 20068230, 33214551, ...28510447, 35138101, 34019948, 30379171, 34725712, 27114449, 29351928, 35132862, 22661428, 31492838, 35254053, 35289036, 30620550, 28657654, 30059200
R917	Methylation	score2	PhosphoSitePlus UniProt	24129315
R927	Methylation	score2	PhosphoSitePlus UniProt	24129315
R938	Methylation	score2	PhosphoSitePlus UniProt	24129315
R967	Methylation	score1	PhosphoSitePlus
R981	Methylation	score1	PhosphoSitePlus
R988	Methylation	score1	PhosphoSitePlus
R1062	Methylation	score1	PhosphoSitePlus
R1073	Methylation	score1	PhosphoSitePlus
K1091	Ubiquitination	score1	PhosphoSitePlus
R1120	Methylation	score1	PhosphoSitePlus
R1122	Methylation	score1	PhosphoSitePlus
R1124	Methylation	score1	PhosphoSitePlus
R1129	Methylation	score1	PhosphoSitePlus
R1133	Methylation	score1	PhosphoSitePlus
R1139	Methylation	score1	PhosphoSitePlus
Y1198	Phosphorylation	score1	PhosphoSitePlus
Y1237	Phosphorylation	score1	PhosphoSitePlus

Search:

Site Select all By amino acid All Serine All Threonine By position S447 T614 T615 S617 T619	PTM Type Select all Phosphorylation	Score Select all 0	Source Select all HPRD	PMID
S447	Phosphorylation	score0	HPRD	19651622
T614	Phosphorylation	score0	HPRD	19651622
T615	Phosphorylation	score0	HPRD	17525332, 18077418, 20068231
S617	Phosphorylation	score0	HPRD	19413330, 17322306, 18077418, ...19664994, 19664995, 18452278, 19651622, 18669648, 20068231
T619	Phosphorylation	score0	HPRD	19413330, 19651622

PTM sites affected in variants

Search:

Site Select all By amino acid All Serine All Threonine By position S22 S445 S447 K542 T611 T614 S617 S686 S822 S861 R927 R938 R967 R981 R1122 R1124 R1129 R1133 R1139	Variant Select all * C927 G967 I822 I981 K1122 K938 L22 L445 L447 L686 M542 M611 N617 N861 Q1129 Q1139 R614 W1124	Source Select all Biomuta	Disease [Sample source] Select all DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:263 / kidney cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S22	L22	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
S445	L445	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
S447	*	Biomuta	DOID:5041 / esophageal cancer [ cosmic ]
S447	L447	Biomuta	DOID:1324 / lung cancer [ cosmic ]
K542	M542	Biomuta	DOID:263 / kidney cancer [ cosmic, icgc ]
T611	M611	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
T614	R614	Biomuta	DOID:1612 / breast cancer [ cosmic, icgc ]
S617	N617	Biomuta	DOID:9256 / colorectal cancer [ cosmic, icgc ]
S686	L686	Biomuta	DOID:3571 / liver cancer [ cosmic ]
S686	*	Biomuta	DOID:1324 / lung cancer [ cosmic ]
S822	I822	Biomuta	DOID:363 / uterine cancer [ icgc ]
S861	N861	Biomuta	DOID:10534 / stomach cancer [ cosmic ]
R927	C927	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
R938	K938	Biomuta	DOID:1612 / breast cancer [ cosmic, icgc ]
R967	G967	Biomuta	DOID:10283 / prostate cancer [ cosmic ]
R981	I981	Biomuta	DOID:10534 / stomach cancer [ cosmic, icgc ]
R1122	K1122	Biomuta	DOID:4606 / bile duct cancer [ cosmic ]
R1124	W1124	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
R1129	Q1129	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
R1129	*	Biomuta	DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
R1133	*	Biomuta	DOID:1324 / lung cancer [ cosmic ]
R1139	Q1139	Biomuta	DOID:10283 / prostate cancer [ cosmic ]

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for Q9UPN6 (SCAF8)

Protein Information

Interactive Sequence View

Q9UPN6 (SCAF8) as Substrate

PTM sites affected in variants