iPTMnet Report for Q9UNY4 (TTF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UNY4 / TTF2_HUMAN
Protein Name Transcription termination factor 2
Gene Name Name: TTF2
Organism Homo sapiens (Human)

PRO ID PR:Q9UNY4
DAG View
PRO Name transcription termination factor 2 (human)
Definition A transcription termination factor 2 that is encoded in the genome of human.
Short Label hTTF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UNY4 (TTF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K16 Ubiquitination PhosphoSitePlus
Y30 Phosphorylation PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K176 Acetylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
S251 Phosphorylation PhosphoSitePlus
Y285 Phosphorylation PhosphoSitePlus
T286 Phosphorylation PhosphoSitePlus
T349 Phosphorylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus
T380 Phosphorylation PhosphoSitePlus
R389 Methylation PhosphoSitePlus
S390 Phosphorylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus
S399 Phosphorylation PhosphoSitePlus
S402 Phosphorylation PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
Y416 Phosphorylation PhosphoSitePlus
K422 Ubiquitination PhosphoSitePlus
K425 Ubiquitination PhosphoSitePlus
K439 Ubiquitination PhosphoSitePlus
K445 Ubiquitination PhosphoSitePlus
S455 Phosphorylation PhosphoSitePlus
S460 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
K468 Ubiquitination PhosphoSitePlus
K481 Ubiquitination PhosphoSitePlus
T500 Phosphorylation PhosphoSitePlus
S505 Phosphorylation PhosphoSitePlus
C512 Methylation IEDB 31844290
S520 Phosphorylation PhosphoSitePlus
Y523 Phosphorylation PhosphoSitePlus
K537 Ubiquitination PhosphoSitePlus
K567 Ubiquitination PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
K624 Ubiquitination PhosphoSitePlus
K657 Ubiquitination PhosphoSitePlus
K662 Ubiquitination PhosphoSitePlus
K707 Ubiquitination PhosphoSitePlus
K743 Ubiquitination PhosphoSitePlus
K755 Ubiquitination PhosphoSitePlus
S810 Phosphorylation PhosphoSitePlus
T813 Phosphorylation PhosphoSitePlus
K814 Ubiquitination PhosphoSitePlus
K822 Ubiquitination PhosphoSitePlus
K839 Ubiquitination PhosphoSitePlus
S868 Phosphorylation PhosphoSitePlus
Y869 Phosphorylation PhosphoSitePlus
K871 Ubiquitination PhosphoSitePlus
R876 Methylation PhosphoSitePlus
S883 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
R890 Methylation PhosphoSitePlus
S908 Phosphorylation PhosphoSitePlus   UniProt 20068231
S918 Phosphorylation PhosphoSitePlus
K992 Ubiquitination PhosphoSitePlus
K1011 Ubiquitination PhosphoSitePlus
T1019 Phosphorylation PhosphoSitePlus
K1030 Ubiquitination PhosphoSitePlus
K1031 Ubiquitination PhosphoSitePlus
Y1036 Phosphorylation PhosphoSitePlus
K1046 Ubiquitination PhosphoSitePlus
K1109 Ubiquitination PhosphoSitePlus
K1125 Ubiquitination PhosphoSitePlus
K1132 Ubiquitination PhosphoSitePlus
K1138 Ubiquitination PhosphoSitePlus
K1150 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S251 Phosphorylation HPRD 20068231
S368 Phosphorylation HPRD 19664994
S374 Phosphorylation HPRD 20068231
T380 Phosphorylation HPRD 20068231
S396 Phosphorylation HPRD 20068231, 17924679
S402 Phosphorylation HPRD 20068231
S460 Phosphorylation HPRD 18691976, 18669648, 20068231
T465 Phosphorylation HPRD 20068231
T500 Phosphorylation HPRD 20068231
S810 Phosphorylation HPRD 20068231
S883 Phosphorylation HPRD 18669648, 20068231
S908 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
K633 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S244 R244 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T286 S286 Biomuta DOID:1324 / lung cancer [ cosmic ]
T380 R380 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T380 M380 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:3571 / liver cancer [ cosmic ]
R389 * Biomuta DOID:3571 / liver cancer [ cosmic ]
R389 Q389 Biomuta DOID:4159 / skin cancer [ cosmic ]
S399 L399 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K439 N439 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K468 N468 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S520 N520 Biomuta DOID:3571 / liver cancer [ cosmic ]
K567 M567 Biomuta DOID:5158 / pleural cancer [ cosmic ]
K624 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T813 A813 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K814 R814 Biomuta DOID:1324 / lung cancer [ cosmic ]
K839 Q839 Biomuta DOID:4159 / skin cancer [ cosmic ]
K839 * Biomuta DOID:263 / kidney cancer [ cosmic ]
S868 F868 Biomuta DOID:4159 / skin cancer [ cosmic ]
K871 Q871 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S883 N883 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S883 G883 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S908 * Biomuta DOID:4362 / cervical cancer [ cosmic ]
S918 F918 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K1150 E1150 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K1150 N1150 Biomuta DOID:1324 / lung cancer [ cosmic ]