Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9UNQ0 / ABCG2_HUMAN
Protein Name Broad substrate specificity ATP-binding cassette transporter ABCG2
Gene Name Name: ABCG2
Organism Homo sapiens (Human)

DAG View
PRO Name ATP-binding cassette sub-family G member 2 (human)
Definition An ATP-binding cassette sub-family G member 2 that is encoded in the genome of human.
Short Label hABCG2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9UNQ0 (ABCG2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S50 Phosphorylation PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
T194 Phosphorylation PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
T362 Phosphorylation P11309 (PIM1) PhosphoSitePlus   RLIMS-P   UniProt 18056989
Y464 Phosphorylation PhosphoSitePlus
N596 N-Glycosylation UniProt 15807535, 28554189
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 20068231
S65 Phosphorylation HPRD 20068231
S100 Phosphorylation HPRD 20068231
S103 Phosphorylation HPRD 20068231

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S65 L65 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ] DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:11054 / urinary bladder cancer [ tcga ]
K172 Q172 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
K323 E323 Biomuta DOID:363 / uterine cancer [ tcga ]
Y464 * Biomuta DOID:1324 / lung cancer [ cosmic ]