iPTMnet Report for Q9UNP9 (PPIE)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UNP9 / PPIE_HUMAN
Protein Name Peptidyl-prolyl cis-trans isomerase E
Gene Name Name: PPIE
Synonyms:CYP33;
Organism Homo sapiens (Human)

PRO ID PR:Q9UNP9
DAG View
PRO Name peptidyl-prolyl cis-trans isomerase E (human)
Definition A peptidyl-prolyl cis-trans isomerase E that is encoded in the genome of human.
Short Label hPPIE
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UNP9 (PPIE) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y41 Phosphorylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K88 Sumoylation PhosphoSitePlus
S91 O-Glycosylation GlyGen 28510447, 36580660, 33465208, ...29351928
S91 Phosphorylation PhosphoSitePlus   UniProt 23186163
S97 Phosphorylation PhosphoSitePlus   UniProt 23186163
K103 Ubiquitination PhosphoSitePlus
K108 Sumoylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus   UniProt 24275569
T126 Phosphorylation PhosphoSitePlus
Y143 Phosphorylation PhosphoSitePlus
C174 Methylation IEDB 31844290
K185 Methylation PhosphoSitePlus
K212 Acetylation PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
T243 O-Glycosylation GlyGen 28510447, 36580660, 33465208, ...29351928
T251 O-Glycosylation GlyGen 28510447, 36580660, 33465208, ...29351928
T251 Phosphorylation PhosphoSitePlus
K254 Methylation PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
C297 Methylation IEDB 31844290
Site PTM Type PTM Enzyme Score Source PMID
T126 Phosphorylation HPRD 18077418
Site PTM Type PTM Enzyme Score Source PMID
T126 Phosphorylation HPRD 18077418
Site PTM Type PTM Enzyme Score Source PMID
K308 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K185 N185 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T243 A243 Biomuta [ cosmic ]