iPTMnet Report for Q9UNN5 (FAF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UNN5 / FAF1_HUMAN
Protein Name FAS-associated factor 1
Gene Name Name: FAF1
Synonyms:UBXD12,UBXN3A;ORFNames:CGI-03;
Organism Homo sapiens (Human)

PRO ID PR:Q9UNN5
DAG View
PRO Name FAS-associated factor 1 (human)
Definition A FAS-associated factor 1 that is encoded in the genome of human.
Short Label hFAF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UNN5 (FAF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S70 O-Glycosylation GlyGen 23301498, 32119511, 34019948, ...28510447, 29351928
S80 O-Glycosylation GlyGen 23301498, 32119511, 34019948, ...28510447, 29351928
K139 Ubiquitination PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
K146 Acetylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K157 Acetylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
Y225 Phosphorylation PhosphoSitePlus
T264 Phosphorylation PhosphoSitePlus
S269 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus   RLIMS-P 28443643
T274 Phosphorylation PhosphoSitePlus
S289 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 11713579, 12832043, 11378439, ...18790738
S289 Phosphorylation O14965 (AURKA) PhosphoSitePlus   Signor 18790738
S289 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 12832043
S291 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 11713579, 12832043, 11378439, ...18790738
S291 Phosphorylation O14965 (AURKA) PhosphoSitePlus   Signor 18790738
S291 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 12832043
K319 Ubiquitination PhosphoSitePlus
S320 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18669648, 28443643, 19690332, ...20068231
S342 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
C348 Methylation IEDB 31844290
K444 Ubiquitination PhosphoSitePlus
K457 Ubiquitination PhosphoSitePlus
K508 Sumoylation PhosphoSitePlus
K544 Ubiquitination PhosphoSitePlus
S556 Phosphorylation PhosphoSitePlus
K566 Ubiquitination PhosphoSitePlus
K575 Ubiquitination PhosphoSitePlus
T580 Phosphorylation PhosphoSitePlus   UniProt 23186163
S582 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 28443643, 23186163
K631 Ubiquitination PhosphoSitePlus
K637 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S153 Phosphorylation HPRD 20068231
Y225 Phosphorylation HPRD 15592455
S270 Phosphorylation HPRD 19651622, 20068231
T274 Phosphorylation HPRD 20068231
S289 Phosphorylation HPRD 11713579, 11378439
S289 Phosphorylation P68400 (CSNK2A1) HPRD 11713579, 11378439
S291 Phosphorylation HPRD 11713579, 11378439
S291 Phosphorylation P68400 (CSNK2A1) HPRD 11713579, 11378439
S320 Phosphorylation HPRD 18669648, 20068231
S582 Phosphorylation HPRD 19651622, 19664994, 20068231
Site PTM Type PTM Enzyme Score Source PMID
T428 Phosphorylation PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S70 T70 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K139 E139 Biomuta DOID:4159 / skin cancer [ cosmic ]
S153 C153 Biomuta DOID:263 / kidney cancer [ cosmic ]
K163 N163 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T580 N580 Biomuta DOID:3571 / liver cancer [ cosmic ]
S582 N582 Biomuta DOID:363 / uterine cancer [ icgc ]