iPTMnet Report for Q9UNI6 (DUSP12)
Protein Information
| UniProt AC / UniProt ID | Q9UNI6 / DUS12_HUMAN |
| Protein Name | Dual specificity protein phosphatase 12 |
| Gene Name | Name: DUSP12 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UNI6 |
| PRO Name | dual specificity protein phosphatase 12 (human) |
| Definition | A dual specificity protein phosphatase 12 that is encoded in the genome of human. |
| Short Label | hDUSP12 |
| Category | organism-gene |
DAG ViewQ9UNI6 (DUSP12) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 19413330, 22814378, 22223895 | ||
| K140 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K144 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K149 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y179 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S241 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K249 | Acetylation | score1 | PhosphoSitePlus | |||
| T252 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T258 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T259 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| T314 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S335 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 21521943, 23186163 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S241 | R241 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K249 | R249 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] |
