iPTMnet Report for Q9UNH5 (CDC14A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UNH5 / CC14A_HUMAN
Protein Name Dual specificity protein phosphatase CDC14A
Gene Name Name: CDC14A
Organism Homo sapiens (Human)

PRO ID PR:Q9UNH5
DAG View
PRO Name dual specificity protein phosphatase CDC14A (human)
Definition A dual specificity protein phosphatase CDC14A that is encoded in the genome of human.
Short Label hCDC14A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UNH5 (CDC14A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K69 Ubiquitination PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
Y84 Phosphorylation PhosphoSitePlus
T85 Phosphorylation PhosphoSitePlus
T222 Phosphorylation PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
S351 Phosphorylation RLIMS-P 19390576
S363 Phosphorylation RLIMS-P 19390576
S411 Phosphorylation PhosphoSitePlus   RLIMS-P 30089874
K422 Methylation PhosphoSitePlus
S429 Phosphorylation PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
S441 Phosphorylation PhosphoSitePlus
T444 Phosphorylation PhosphoSitePlus
T447 Phosphorylation PhosphoSitePlus
S453 Phosphorylation PhosphoSitePlus   RLIMS-P 30089874
S465 Phosphorylation PhosphoSitePlus
S476 Phosphorylation PhosphoSitePlus
S484 Phosphorylation PhosphoSitePlus   UniProt 23186163
S549 Phosphorylation PhosphoSitePlus   RLIMS-P 30089874
S583 Phosphorylation IEDB   PhosphoSitePlus   UniProt 32387766, 23186163
S589 Phosphorylation PhosphoSitePlus
Y591 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S381 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y84 F84 Biomuta DOID:1324 / lung cancer [ cosmic ]
S348 I348 Biomuta DOID:1324 / lung cancer [ cosmic ]
K422 N422 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T444 I444 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T444 S444 Biomuta DOID:4159 / skin cancer [ cosmic ]
S465 F465 Biomuta DOID:4159 / skin cancer [ cosmic ]
S549 I549 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
Y591 * Biomuta DOID:3571 / liver cancer [ cosmic ]