iPTMnet Report for Q9UNE0 (EDAR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UNE0 / EDAR_HUMAN
Protein Name Tumor necrosis factor receptor superfamily member EDAR precursor
Gene Name Name: EDAR
Synonyms:DL;
Organism Homo sapiens (Human)

PRO ID PR:Q9UNE0
DAG View
PRO Name tumor necrosis factor receptor superfamily member EDAR (human)
Definition A tumor necrosis factor receptor superfamily member EDAR that is encoded in the genome of human.
Short Label hEDAR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UNE0 (EDAR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T100 O-Glycosylation GlyGen 25813380
S153 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
S286 Phosphorylation PhosphoSitePlus
S324 Phosphorylation phospho.ELM 14729942
S357 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
T363 Phosphorylation PhosphoSitePlus
Y364 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
S402 Phosphorylation PhosphoSitePlus
Y406 Phosphorylation PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S324 Phosphorylation HPRD 14729942


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S153 L153 Biomuta DOID:1324 / lung cancer [ cosmic ]
S324 N324 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S357 N357 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y364 H364 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S366 F366 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic ]
S407 R407 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S407 I407 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]