iPTMnet Report for Q9UN30 (SCML1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UN30 / SCML1_HUMAN
Protein Name Sex comb on midleg-like protein 1
Gene Name Name: SCML1
Organism Homo sapiens (Human)

PRO ID PR:Q9UN30
DAG View
PRO Name sex comb on midleg-like protein 1 (human)
Definition A sex comb on midleg-like protein 1 that is encoded in the genome of human.
Short Label hSCML1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UN30 (SCML1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T18 Phosphorylation PhosphoSitePlus
Y19 Phosphorylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus   UniProt 18669648
T140 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
S152 Phosphorylation PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus   UniProt 18691976
K307 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S15 Phosphorylation HPRD 18669648
S17 Phosphorylation HPRD 18669648, 18452278
S55 Phosphorylation HPRD 18452278
S117 Phosphorylation HPRD 18691976, 18452278
Site PTM Type PTM Enzyme Score Source PMID
S109 Phosphorylation HPRD 18669648
S111 Phosphorylation HPRD 18669648, 18452278
S149 Phosphorylation HPRD 18452278
S211 Phosphorylation HPRD 18691976, 18452278
Site PTM Type PTM Enzyme Score Source PMID
S136 Phosphorylation HPRD 18669648
S138 Phosphorylation HPRD 18669648, 18452278
S176 Phosphorylation HPRD 18452278
S238 Phosphorylation HPRD 18691976, 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S17 C17 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y19 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S111 C111 Biomuta DOID:3571 / liver cancer [ cosmic ]
K121 Q121 Biomuta DOID:363 / uterine cancer [ icgc ]
S138 C138 Biomuta DOID:3571 / liver cancer [ cosmic ]
S150 F150 Biomuta DOID:4159 / skin cancer [ cosmic ]
S218 N218 Biomuta DOID:9256 / colorectal cancer [ icgc ]