iPTMnet Report for Q9UMY4 (SNX12)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UMY4 / SNX12_HUMAN
Protein Name Sorting nexin-12
Gene Name Name: SNX12
Organism Homo sapiens (Human)

PRO ID PR:Q9UMY4
DAG View
PRO Name sorting nexin-12 (human)
Definition A sorting nexin-12 that is encoded in the genome of human.
Short Label hSNX12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UMY4 (SNX12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 22814378
S2 Phosphorylation PhosphoSitePlus
R10 Methylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
Y23 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15592455
S27 Phosphorylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
Y72 Phosphorylation PhosphoSitePlus
S73 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983
K79 Ubiquitination PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
S114 Phosphorylation PhosphoSitePlus
R153 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K159 Ubiquitination PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
S169 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y23 Phosphorylation HPRD 15592455
S73 Phosphorylation HPRD 19651622, 20166139, 18669648, ...17081983, 20068231
Site PTM Type PTM Enzyme Score Source PMID
K155 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R10 Q10 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R10 W10 Biomuta DOID:363 / uterine cancer [ icgc ]
K87 R87 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K87 N87 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S114 C114 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R153 K153 Biomuta [ cosmic ]