iPTMnet Report for Q9UMW8 (USP18)
Protein Information
| UniProt AC / UniProt ID | Q9UMW8 / UBP18_HUMAN |
| Protein Name | Ubl carboxyl-terminal hydrolase 18 |
| Gene Name | Name: USP18 Synonyms:ISG43; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UMW8 |
| PRO Name | Ubl carboxyl-terminal hydrolase 18 (human) |
| Definition | A Ubl carboxyl-terminal hydrolase 18 that is encoded in the genome of human. |
| Short Label | hUSP18 |
| Category | organism-gene |
DAG ViewQ9UMW8 (USP18) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K3 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y125 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K173 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C178 | Methylation | score1 | IEDB | 31844290 | ||
| S264 | Phosphorylation | score1 | IEDB | 29493099 | ||
| K268 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K288 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K173 | R173 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K173 | N173 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
