Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UMR2 / DD19B_HUMAN
Protein Name ATP-dependent RNA helicase DDX19B
Gene Name Name: DDX19B
Synonyms:DBP5,DDX19,TDBP;
Organism Homo sapiens (Human)

PRO ID PR:Q9UMR2
DAG View
PRO Name ATP-dependent RNA helicase DDX19B (human)
Definition An ATP-dependent RNA helicase DDX19B that is encoded in the genome of human.
Short Label hDDX19B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UMR2 (DDX19B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22223895
S19 Phosphorylation PhosphoSitePlus
T48 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
S86 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y89 Phosphorylation phospho.ELM 18669648
S90 Phosphorylation phospho.ELM 18669648
K92 Ubiquitination PhosphoSitePlus
S93 Phosphorylation O14757 (CHEK1) PhosphoSitePlus 21851590
S154 Phosphorylation PhosphoSitePlus
K187 Acetylation PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
R199 Methylation PhosphoSitePlus
K202 Acetylation PhosphoSitePlus
K229 Acetylation PhosphoSitePlus
K287 Acetylation PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
T422 Phosphorylation PhosphoSitePlus
Y423 Phosphorylation PhosphoSitePlus
S445 Phosphorylation PhosphoSitePlus
T468 Phosphorylation PhosphoSitePlus
K476 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S86 Phosphorylation HPRD 18669648
Y89 Phosphorylation HPRD 18669648
S90 Phosphorylation HPRD 18669648
S354 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S86 Phosphorylation HPRD 18669648
Y89 Phosphorylation HPRD 18669648
S90 Phosphorylation HPRD 18669648
S93 Phosphorylation PhosphoSitePlus
S323 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S245 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S60 P60 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y89 N89 Biomuta DOID:2531 / hematologic cancer [ tcga ]
S90 L90 Biomuta DOID:1324 / lung cancer [ tcga ]
K187 T187 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K193 Q193 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
R199 * Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
K308 N308 Biomuta DOID:3571 / liver cancer [ icgc ]