iPTMnet Report for Q9UMR2 (DDX19B)
Protein Information
| UniProt AC / UniProt ID | Q9UMR2 / DD19B_HUMAN |
| Protein Name | ATP-dependent RNA helicase DDX19B |
| Gene Name | Name: DDX19B Synonyms:DBP5,DDX19,TDBP; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UMR2 |
| PRO Name | ATP-dependent RNA helicase DDX19B (human) |
| Definition | An ATP-dependent RNA helicase DDX19B that is encoded in the genome of human. |
| Short Label | hDDX19B |
| Category | organism-gene |
Q9UMR2 (DDX19B) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 22223895 | ||
| S19 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T48 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S60 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K64 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S86 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| Y89 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
| S90 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
| K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S93 | Phosphorylation | O14757 (CHEK1) | score1 | PhosphoSitePlus | 21851590 | |
| S154 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K187 | Acetylation | score1 | PhosphoSitePlus | |||
| K187 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K193 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R199 | Methylation | score1 | PhosphoSitePlus | |||
| K202 | Acetylation | score1 | PhosphoSitePlus | |||
| K229 | Acetylation | score1 | PhosphoSitePlus | |||
| K287 | Acetylation | score1 | PhosphoSitePlus | |||
| K287 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K308 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T422 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y423 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S445 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T468 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K476 | Ubiquitination | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S86 | Phosphorylation | score0 | HPRD | 18669648 | ||
| Y89 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S90 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S354 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S60 | P60 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| Y89 | C89 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, cosmic ] | |
| K187 | T187 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K193 | Q193 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| R199 | Q199 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| R199 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View