iPTMnet Report for Q9UMR2 (DDX19B)
Protein Information
UniProt AC / UniProt ID | Q9UMR2 / DD19B_HUMAN |
Protein Name | ATP-dependent RNA helicase DDX19B |
Gene Name | Name: DDX19B Synonyms:DBP5,DDX19,TDBP; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UMR2 |
PRO Name | ATP-dependent RNA helicase DDX19B (human) |
Definition | An ATP-dependent RNA helicase DDX19B that is encoded in the genome of human. |
Short Label | hDDX19B |
Category | organism-gene |
Q9UMR2 (DDX19B) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22223895 | ||
S19 | Phosphorylation | score1 | PhosphoSitePlus | |||
T48 | Phosphorylation | score1 | PhosphoSitePlus | |||
S60 | Phosphorylation | score1 | PhosphoSitePlus | |||
K64 | Ubiquitination | score1 | PhosphoSitePlus | |||
S86 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
Y89 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
S90 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
S93 | Phosphorylation | O14757 (CHEK1) | score1 | PhosphoSitePlus | 21851590 | |
S154 | Phosphorylation | score1 | PhosphoSitePlus | |||
K187 | Acetylation | score1 | PhosphoSitePlus | |||
K187 | Ubiquitination | score1 | PhosphoSitePlus | |||
K193 | Ubiquitination | score1 | PhosphoSitePlus | |||
R199 | Methylation | score1 | PhosphoSitePlus | |||
K202 | Acetylation | score1 | PhosphoSitePlus | |||
K229 | Acetylation | score1 | PhosphoSitePlus | |||
K287 | Acetylation | score1 | PhosphoSitePlus | |||
K287 | Ubiquitination | score1 | PhosphoSitePlus | |||
K308 | Ubiquitination | score1 | PhosphoSitePlus | |||
T422 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y423 | Phosphorylation | score1 | PhosphoSitePlus | |||
S445 | Phosphorylation | score1 | PhosphoSitePlus | |||
T468 | Phosphorylation | score1 | PhosphoSitePlus | |||
K476 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S86 | Phosphorylation | score0 | HPRD | 18669648 | ||
Y89 | Phosphorylation | score0 | HPRD | 18669648 | ||
S90 | Phosphorylation | score0 | HPRD | 18669648 | ||
S354 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S60 | P60 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
Y89 | C89 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, cosmic ] | |
K187 | T187 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K193 | Q193 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
R199 | Q199 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
R199 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |