iPTMnet Report for Q9UM21 (MGAT4A)
Protein Information
UniProt AC / UniProt ID | Q9UM21 / MGT4A_HUMAN |
Protein Name | Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A |
Gene Name | Name: MGAT4A |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UM21 |
PRO Name | alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A (human) |
Definition | An alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A that is encoded in the genome of human. |
Short Label | hMGAT4A |
Category | organism-gene |
Q9UM21 (MGAT4A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
S22 | Phosphorylation | score1 | PhosphoSitePlus | |||
S59 | O-Glycosylation | score1 | PhosphoSitePlus | |||
S60 | O-Glycosylation | score1 | PhosphoSitePlus | |||
T64 | O-Glycosylation | score1 | PhosphoSitePlus | |||
N77 | N-Glycosylation | score1 | GlyGen | 23090970, 24190977 | ||
S197 | Phosphorylation | score1 | PhosphoSitePlus | |||
T219 | Phosphorylation | score1 | PhosphoSitePlus | |||
K222 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y255 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y256 | Phosphorylation | score1 | PhosphoSitePlus | |||
K374 | Acetylation | score1 | PhosphoSitePlus | |||
T376 | O-Glycosylation | score1 | PhosphoSitePlus | |||
K378 | Acetylation | score1 | PhosphoSitePlus | |||
K382 | Ubiquitination | score1 | PhosphoSitePlus | |||
S474 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 26091039 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S8 | Phosphorylation | score1 | PhosphoSitePlus | |||
T15 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S8 | L8 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S17 | F17 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S59 | F59 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
Y255 | H255 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |