iPTMnet Report for Q9ULX6 (AKAP8L)
Protein Information
UniProt AC / UniProt ID | Q9ULX6 / AKP8L_HUMAN |
Protein Name | A-kinase anchor protein 8-like |
Gene Name | Name: AKAP8L Synonyms:NAKAP,NAKAP95;ORFNames:HRIHFB2018; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9ULX6 |
PRO Name | A-kinase anchor protein 8-like (human) |
Definition | An A-kinase anchor protein 8-like that is encoded in the genome of human. |
Short Label | hAKAP8L |
Category | organism-gene |
Q9ULX6 (AKAP8L) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y29 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y31 | Phosphorylation | score1 | PhosphoSitePlus | |||
S117 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y125 | Phosphorylation | score1 | PhosphoSitePlus | |||
C128 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
R131 | Methylation | score1 | PhosphoSitePlus | |||
S135 | Phosphorylation | score1 | PhosphoSitePlus | |||
R171 | Methylation | score1 | PhosphoSitePlus | |||
R179 | Methylation | score1 | PhosphoSitePlus | |||
R185 | Methylation | score1 | PhosphoSitePlus | |||
R188 | Methylation | score1 | PhosphoSitePlus | |||
R191 | Methylation | score1 | PhosphoSitePlus | |||
Y197 | Phosphorylation | score1 | PhosphoSitePlus | |||
R199 | Methylation | score1 | PhosphoSitePlus | |||
R208 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
R217 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
R237 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
R247 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
K257 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K257 | Ubiquitination | score1 | PhosphoSitePlus | |||
K264 | Ubiquitination | score1 | PhosphoSitePlus | |||
T267 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T268 | Phosphorylation | score1 | PhosphoSitePlus | |||
R272 | Methylation | score1 | PhosphoSitePlus | |||
S283 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18691976, 15302935, 20068231 | ||
S289 | Phosphorylation | score1 | PhosphoSitePlus | |||
K290 | Ubiquitination | score1 | PhosphoSitePlus | |||
T292 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
T294 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S297 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
S300 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S302 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
T308 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
T313 | Phosphorylation | score1 | PhosphoSitePlus | |||
S326 | Phosphorylation | score1 | PhosphoSitePlus | |||
K362 | Ubiquitination | score1 | PhosphoSitePlus | |||
R397 | Methylation | score1 | PhosphoSitePlus | |||
K411 | Ubiquitination | score1 | PhosphoSitePlus | |||
K414 | Ubiquitination | score1 | PhosphoSitePlus | |||
K418 | Ubiquitination | score1 | PhosphoSitePlus | |||
K423 | Ubiquitination | score1 | PhosphoSitePlus | |||
K426 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y435 | Phosphorylation | score1 | PhosphoSitePlus | |||
K439 | Ubiquitination | score1 | PhosphoSitePlus | |||
K448 | Ubiquitination | score1 | PhosphoSitePlus | |||
K477 | Ubiquitination | score1 | PhosphoSitePlus | |||
K500 | Acetylation | score1 | PhosphoSitePlus | |||
K503 | Ubiquitination | score1 | PhosphoSitePlus | |||
T504 | Phosphorylation | score1 | PhosphoSitePlus | |||
K520 | Acetylation | score1 | PhosphoSitePlus | |||
K533 | Ubiquitination | score1 | PhosphoSitePlus | |||
K544 | Sumoylation | score1 | PhosphoSitePlus | |||
K544 | Ubiquitination | score1 | PhosphoSitePlus | |||
T550 | Phosphorylation | score1 | PhosphoSitePlus | |||
S552 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S601 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y31 | C31 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
R171 | C171 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R185 | G185 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
R188 | W188 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R191 | P191 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
R199 | H199 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] | |
R217 | Q217 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
R217 | W217 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R272 | L272 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S283 | R283 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
S289 | N289 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K290 | E290 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
R397 | W397 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
T504 | I504 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |