iPTMnet Report for Q9ULV8 (CBLC)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9ULV8 / CBLC_HUMAN
Protein Name E3 ubiquitin-protein ligase CBL-C
Gene Name Name: CBLC
Synonyms:CBL3,RNF57;
Organism Homo sapiens (Human)

PRO ID PR:Q9ULV8
DAG View
PRO Name E3 ubiquitin-protein ligase CBL-C (human)
Definition An E3 ubiquitin-protein ligase CBL-C that is encoded in the genome of human.
Short Label hCBLC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9ULV8 (CBLC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S40 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S43 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
T223 Phosphorylation PhosphoSitePlus
Y309 Phosphorylation PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
Y341 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor   UniProt 23145173, 20525694, 24425877
Y341 Phosphorylation P12931 (SRC) PhosphoSitePlus   Signor 20525694, 24425877
Y402 Phosphorylation PhosphoSitePlus
S461 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S40 Phosphorylation HPRD 15302935
S61 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S43 L43 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y309 S309 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y341 C341 Biomuta DOID:1324 / lung cancer [ cosmic ]