iPTMnet Report for Q9ULV5 (HSF4)
Protein Information
| UniProt AC / UniProt ID | Q9ULV5 / HSF4_HUMAN |
| Protein Name | Heat shock factor protein 4 |
| Gene Name | Name: HSF4 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9ULV5 |
| PRO Name | heat shock factor protein 4 (human) |
| Definition | A heat shock factor protein 4 that is encoded in the genome of human. |
| Short Label | hHSF4 |
| Category | organism-gene |
Q9ULV5 (HSF4) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K206 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S280 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
| S281 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
| K287 | Sumoylation | score1 | PhosphoSitePlus | |||
| K293 | Sumoylation | score1 | PhosphoSitePlus | |||
| S298 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 16371476 | ||
| T471 | Phosphorylation | score2 | PhosphoSitePlus | 24361130 | ||
| T471 | Phosphorylation | P52564 (MAP2K6) | score2 | PhosphoSitePlus | 24361130 | |
| S491 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y239 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T273 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S491 | F491 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S491 | P491 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] |
DAG View