iPTMnet Report for Q9ULU4 (ZMYND8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9ULU4 / ZMYD8_HUMAN
Protein Name MYND-type zinc finger-containing chromatin reader ZMYND8
Gene Name Name: ZMYND8
Synonyms:KIAA1125,PRKCBP1,RACK7;
Organism Homo sapiens (Human)

PRO ID PR:Q9ULU4
DAG View
PRO Name protein kinase C-binding protein 1 (human)
Definition A protein kinase C-binding protein 1 that is encoded in the genome of human.
Short Label hZMYND8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9ULU4 (ZMYND8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus   UniProt 23186163
S28 Phosphorylation PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
T37 Phosphorylation PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
K46 Acetylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
K56 Acetylation PhosphoSitePlus
T235 Phosphorylation PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
Y362 Phosphorylation PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus
Y369 Phosphorylation PhosphoSitePlus
T404 Phosphorylation PhosphoSitePlus   UniProt 20068231
S406 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 24275569, ...19690332, 20068231
S412 Phosphorylation PhosphoSitePlus
K413 Acetylation PhosphoSitePlus   UniProt 19608861
S417 Phosphorylation PhosphoSitePlus   UniProt 23186163
T420 Phosphorylation PhosphoSitePlus
S425 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...18220336
S427 Phosphorylation PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus   UniProt 21406692
S435 Phosphorylation PhosphoSitePlus
T436 Phosphorylation PhosphoSitePlus
S438 Phosphorylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
T442 Phosphorylation PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
T455 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S456 Phosphorylation PhosphoSitePlus
S460 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S462 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S465 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S472 Phosphorylation PhosphoSitePlus
S475 Phosphorylation PhosphoSitePlus
T479 Phosphorylation PhosphoSitePlus
T481 Phosphorylation PhosphoSitePlus
S486 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 15302935, 19690332, ...20068231
S488 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S490 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 15302935, 18669648, ...24275569, 19690332
S495 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
S499 Phosphorylation PhosphoSitePlus
T504 O-Glycosylation GlyGen 23301498, 33214551, 30379171, ...32574038, 34725712, 34019948, 35254053, 35132862, 32119511, 22661428
K508 Ubiquitination PhosphoSitePlus
S514 Phosphorylation PhosphoSitePlus   UniProt 23186163
S523 Phosphorylation PhosphoSitePlus   UniProt 23186163
S535 Phosphorylation PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus
T541 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S547 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 15302935, ...18669648, 24275569
R555 Methylation PhosphoSitePlus
T563 Phosphorylation PhosphoSitePlus   UniProt 23186163
S587 Phosphorylation PhosphoSitePlus
S589 Phosphorylation PhosphoSitePlus
S592 Phosphorylation PhosphoSitePlus
S595 Phosphorylation PhosphoSitePlus
S610 Phosphorylation PhosphoSitePlus
K611 Sumoylation PhosphoSitePlus
S630 Phosphorylation PhosphoSitePlus
T639 Phosphorylation PhosphoSitePlus
K645 Sumoylation PhosphoSitePlus
S652 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 15302935
S655 Phosphorylation PhosphoSitePlus   UniProt 23186163
S668 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231, 24275569
S676 Phosphorylation PhosphoSitePlus
S682 Phosphorylation PhosphoSitePlus   UniProt 21406692
T696 Phosphorylation PhosphoSitePlus
S707 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S709 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S711 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S737 Phosphorylation PhosphoSitePlus   UniProt 23186163
T746 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...30379171, 32574038, 34725712, 34019948, 35254053, 35132862, 32119511, 22661428
T746 Phosphorylation PhosphoSitePlus   UniProt 21406692
S749 O-Glycosylation GlyGen 34846842
T750 O-Glycosylation GlyGen 23301498, 33214551, 32938750, ...30379171, 32574038, 34725712, 34019948, 35254053, 35132862, 32119511, 22661428
T750 Phosphorylation PhosphoSitePlus
T751 O-Glycosylation GlyGen 23301498, 33214551, 32938750, ...30379171, 32574038, 34725712, 34019948, 35254053, 35132862, 32119511, 22661428
S754 O-Glycosylation GlyGen 32574038
S754 Phosphorylation PhosphoSitePlus   UniProt 21406692
S756 O-Glycosylation GlyGen 32574038
S756 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692
T760 Phosphorylation PhosphoSitePlus
T764 Phosphorylation PhosphoSitePlus
S771 O-Glycosylation GlyGen 23301498, 33214551, 32938750, ...30379171, 32574038, 34725712, 34019948, 35254053, 35132862, 32119511, 22661428
T776 O-Glycosylation GlyGen 32938750
T779 O-Glycosylation GlyGen 23301498, 33214551, 32938750, ...30379171, 32574038, 34725712, 34019948, 35254053, 35132862, 32119511, 22661428
S780 O-Glycosylation GlyGen 23301498, 33214551, 32938750, ...30379171, 32574038, 34725712, 34019948, 35254053, 35132862, 32119511, 22661428
S797 Phosphorylation PhosphoSitePlus
S1085 O-Glycosylation GlyGen 30620550
S1086 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S1089 Phosphorylation PhosphoSitePlus
T1093 Phosphorylation PhosphoSitePlus
S1114 Phosphorylation PhosphoSitePlus
S1119 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1124 Phosphorylation PhosphoSitePlus
S1141 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1152 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation PhosphoSitePlus
K12 Sumoylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T424 Phosphorylation HPRD 20068231
S426 Phosphorylation HPRD 19413330, 17322306, 20058876, ...19664994, 19691289, 19651622, 18669648, 18767875, 20068231
S432 Phosphorylation HPRD 20068230
T440 Phosphorylation HPRD 20068231, 20068230
S445 Phosphorylation HPRD 19651622, 18669648, 19691289, ...20068231, 18452278
S447 Phosphorylation HPRD 20068231
S452 Phosphorylation HPRD 20068231
S455 Phosphorylation HPRD 18452278
S459 Phosphorylation HPRD 18452278
T462 Phosphorylation HPRD 19651622
S464 Phosphorylation HPRD 20068231
T475 Phosphorylation HPRD 18669648
S480 Phosphorylation HPRD 18669648, 20068231, 18452278
S482 Phosphorylation HPRD 18669648, 20068231
S485 Phosphorylation HPRD 18669648, 20068231
T501 Phosphorylation HPRD 19413330
S506 Phosphorylation HPRD 19413330, 16964243, 15302935, ...20058876, 19664995, 18669648, 20166139, 20068231
S508 Phosphorylation HPRD 19413330, 17081983, 20058876, ...19664995, 19651622, 18669648
S510 Phosphorylation HPRD 19413330, 15302935, 19664995, ...19651622, 18669648, 20166139, 20068231
S515 Phosphorylation HPRD 19413330, 18669648, 16964243, ...20068231
T561 Phosphorylation HPRD 19413330, 18669648, 19664995, ...20068231
S567 Phosphorylation HPRD 19413330, 18669648, 15302935, ...19664995, 20068231
S597 Phosphorylation HPRD 17081983
Y601 Phosphorylation HPRD 17081983
T602 Phosphorylation HPRD 17081983
S609 Phosphorylation HPRD 17081983
S612 Phosphorylation HPRD 17081983
S672 Phosphorylation HPRD 15302935
S688 Phosphorylation HPRD 19651622, 17081983, 20068231
S696 Phosphorylation HPRD 18452278
S702 Phosphorylation HPRD 20068231
S727 Phosphorylation HPRD 18669648, 18452278
S729 Phosphorylation HPRD 18669648, 18452278
S731 Phosphorylation HPRD 18669648, 18452278
S757 Phosphorylation HPRD 19691289, 20068231
S774 Phosphorylation HPRD 19664995
S776 Phosphorylation HPRD 19651622, 18669648, 19664995
S1060 Phosphorylation HPRD 19413330, 17525332, 19664995
S1063 Phosphorylation HPRD 19413330
T1067 Phosphorylation HPRD 19413330
S1098 Phosphorylation HPRD 19691289
Site PTM Type PTM Enzyme Score Source PMID
T424 Phosphorylation HPRD 20068231
S426 Phosphorylation HPRD 19413330, 17322306, 20058876, ...19664994, 19691289, 19651622, 18669648, 18767875, 20068231
S432 Phosphorylation HPRD 20068230
T440 Phosphorylation HPRD 20068231, 20068230
S445 Phosphorylation HPRD 19651622, 18669648, 19691289, ...20068231, 18452278
S447 Phosphorylation HPRD 20068231
S452 Phosphorylation HPRD 20068231
S455 Phosphorylation HPRD 18452278
S459 Phosphorylation HPRD 18452278
T462 Phosphorylation HPRD 19651622
S464 Phosphorylation HPRD 20068231
T475 Phosphorylation HPRD 18669648
S480 Phosphorylation HPRD 18669648, 20068231, 18452278
S482 Phosphorylation HPRD 18669648, 20068231
S485 Phosphorylation HPRD 18669648, 20068231
T501 Phosphorylation HPRD 19413330
S506 Phosphorylation HPRD 19413330, 16964243, 15302935, ...20058876, 19664995, 18669648, 20166139, 20068231
S508 Phosphorylation HPRD 19413330, 17081983, 20058876, ...19664995, 19651622, 18669648
S510 Phosphorylation HPRD 19413330, 15302935, 19664995, ...19651622, 18669648, 20166139, 20068231
S515 Phosphorylation HPRD 19413330, 18669648, 16964243, ...20068231
T561 Phosphorylation HPRD 19413330, 18669648, 19664995, ...20068231
S567 Phosphorylation HPRD 19413330, 18669648, 15302935, ...19664995, 20068231
S597 Phosphorylation HPRD 17081983
Y601 Phosphorylation HPRD 17081983
T602 Phosphorylation HPRD 17081983
S609 Phosphorylation HPRD 17081983
S612 Phosphorylation HPRD 17081983
S672 Phosphorylation HPRD 15302935
S688 Phosphorylation HPRD 19651622, 17081983, 20068231
S696 Phosphorylation HPRD 18452278
S702 Phosphorylation HPRD 20068231
S727 Phosphorylation HPRD 18669648, 18452278
S729 Phosphorylation HPRD 18669648, 18452278
S731 Phosphorylation HPRD 18669648, 18452278
S757 Phosphorylation HPRD 19691289, 20068231
S774 Phosphorylation HPRD 19664995
S776 Phosphorylation HPRD 19651622, 18669648, 19664995
S1060 Phosphorylation HPRD 19413330, 17525332, 19664995
S1063 Phosphorylation HPRD 19413330
T1067 Phosphorylation HPRD 19413330
S1098 Phosphorylation HPRD 19691289
S1115 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation PhosphoSitePlus
K12 Sumoylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
S73 Phosphorylation PhosphoSitePlus
T399 Phosphorylation HPRD 20068231
S401 Phosphorylation HPRD 19413330, 17322306, 20058876, ...19664994, 19691289, 19651622, 18669648, 18767875, 20068231
S407 Phosphorylation HPRD 20068230
T415 Phosphorylation HPRD 20068231, 20068230
S420 Phosphorylation HPRD 19651622, 18669648, 19691289, ...20068231, 18452278
S422 Phosphorylation HPRD 20068231
S427 Phosphorylation HPRD 20068231
S430 Phosphorylation HPRD 18452278
S434 Phosphorylation HPRD 18452278
T437 Phosphorylation HPRD 19651622
S439 Phosphorylation HPRD 20068231
T450 Phosphorylation HPRD 18669648
S455 Phosphorylation HPRD 18669648, 20068231, 18452278
S457 Phosphorylation HPRD 18669648, 20068231
S460 Phosphorylation HPRD 18669648, 20068231
T476 Phosphorylation HPRD 19413330
S481 Phosphorylation HPRD 19413330, 16964243, 15302935, ...20058876, 19664995, 18669648, 20166139, 20068231
S483 Phosphorylation HPRD 19413330, 17081983, 20058876, ...19664995, 19651622, 18669648
S485 Phosphorylation HPRD 19413330, 15302935, 19664995, ...19651622, 18669648, 20166139, 20068231
S490 Phosphorylation HPRD 19413330, 18669648, 16964243, ...20068231
T536 Phosphorylation HPRD 19413330, 18669648, 19664995, ...20068231
S542 Phosphorylation HPRD 19413330, 18669648, 15302935, ...19664995, 20068231
S572 Phosphorylation HPRD 17081983
Y576 Phosphorylation HPRD 17081983
T577 Phosphorylation HPRD 17081983
S584 Phosphorylation HPRD 17081983
S587 Phosphorylation HPRD 17081983
S647 Phosphorylation HPRD 15302935
S663 Phosphorylation HPRD 19651622, 17081983, 20068231
S671 Phosphorylation HPRD 18452278
S677 Phosphorylation HPRD 20068231
S702 Phosphorylation HPRD 18669648, 18452278
S704 Phosphorylation HPRD 18669648, 18452278
S706 Phosphorylation HPRD 18669648, 18452278
S732 Phosphorylation HPRD 19691289, 20068231
S749 Phosphorylation HPRD 19664995
S751 Phosphorylation HPRD 19651622, 18669648, 19664995
S1035 Phosphorylation HPRD 19413330, 17525332, 19664995
S1038 Phosphorylation HPRD 19413330
T1042 Phosphorylation HPRD 19413330
S1073 Phosphorylation HPRD 19691289
Site PTM Type PTM Enzyme Score Source PMID
S950 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S53 N53 Biomuta DOID:363 / uterine cancer [ icgc ]
S73 N73 Biomuta DOID:363 / uterine cancer [ icgc ]
Y369 H369 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:184 / bone cancer [ cosmic ] DOID:1612 / breast cancer [ icgc ] DOID:11054 / urinary bladder cancer [ cosmic ]
T399 M399 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S401 P401 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T404 M404 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S406 P406 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S420 F420 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S422 P422 Biomuta DOID:1612 / breast cancer [ cosmic ]
T424 M424 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S425 F425 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S426 P426 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S427 P427 Biomuta DOID:1612 / breast cancer [ cosmic ]
T437 M437 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S439 F439 Biomuta DOID:4159 / skin cancer [ cosmic ]
S439 C439 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T442 M442 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S444 F444 Biomuta DOID:4159 / skin cancer [ cosmic ]
S444 C444 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S445 F445 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S447 P447 Biomuta DOID:1612 / breast cancer [ cosmic ]
T450 M450 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T455 M455 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S456 L456 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T462 M462 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S464 C464 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S464 F464 Biomuta DOID:4159 / skin cancer [ cosmic ]
S472 I472 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S472 G472 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T475 M475 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T476 M476 Biomuta DOID:4159 / skin cancer [ cosmic ]
T481 M481 Biomuta DOID:4159 / skin cancer [ cosmic ]
T501 M501 Biomuta DOID:4159 / skin cancer [ cosmic ]
K508 R508 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S535 * Biomuta DOID:263 / kidney cancer [ cosmic ]
S535 L535 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S572 L572 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T577 M577 Biomuta DOID:1324 / lung cancer [ cosmic ]
S584 L584 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S589 L589 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S595 L595 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S597 L597 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T602 M602 Biomuta DOID:1324 / lung cancer [ cosmic ]
S609 L609 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S630 C630 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S655 N655 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S677 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S682 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
T696 M696 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S702 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S706 G706 Biomuta DOID:184 / bone cancer [ cosmic ]
S711 G711 Biomuta DOID:184 / bone cancer [ cosmic ]
S731 G731 Biomuta DOID:184 / bone cancer [ cosmic ]
T746 I746 Biomuta [ cosmic ]
T750 S750 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S751 C751 Biomuta DOID:1612 / breast cancer [ icgc ]
T751 M751 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S756 C756 Biomuta DOID:1612 / breast cancer [ icgc ]
S776 C776 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1612 / breast cancer [ icgc ]
S780 N780 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1073 F1073 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1098 F1098 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1115 F1115 Biomuta DOID:4159 / skin cancer [ cosmic, cosmic, icgc, cosmic, cosmic, cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, cosmic, cosmic, icgc, cosmic, cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
S1124 F1124 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1141 F1141 Biomuta DOID:4159 / skin cancer [ cosmic ]