iPTMnet Report for Q9ULT0 (TTC7A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9ULT0 / TTC7A_HUMAN
Protein Name Tetratricopeptide repeat protein 7A
Gene Name Name: TTC7A
Synonyms:KIAA1140;
Organism Homo sapiens (Human)

PRO ID PR:Q9ULT0
DAG View
PRO Name tetratricopeptide repeat protein 7A (human)
Definition A tetratricopeptide repeat protein 7A that is encoded in the genome of human.
Short Label hTTC7A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9ULT0 (TTC7A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K4 Ubiquitination PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
K12 Ubiquitination PhosphoSitePlus
S51 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18669648, ...19690332, 20068231
S53 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
T57 Phosphorylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
Y160 Phosphorylation PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
N181 N-Glycosylation GlyGen 24190977
S182 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus   UniProt 32387766, 18669648, 23186163
S185 Phosphorylation PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
Y396 Phosphorylation PhosphoSitePlus
S400 Phosphorylation PhosphoSitePlus
K516 Ubiquitination PhosphoSitePlus
K560 Ubiquitination PhosphoSitePlus
S647 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 20068231, 23186163, 17081983, ...24275569
K655 Ubiquitination PhosphoSitePlus
K656 Ubiquitination PhosphoSitePlus
S658 Phosphorylation PhosphoSitePlus
S672 Phosphorylation PhosphoSitePlus
S678 Phosphorylation PhosphoSitePlus
S679 Phosphorylation PhosphoSitePlus
S690 Phosphorylation PhosphoSitePlus   UniProt 23186163
T693 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S697 Phosphorylation PhosphoSitePlus
C733 Methylation IEDB 31844290
K758 Ubiquitination PhosphoSitePlus
K765 Ubiquitination PhosphoSitePlus
K769 Ubiquitination PhosphoSitePlus
K795 Ubiquitination PhosphoSitePlus
K800 Ubiquitination PhosphoSitePlus
C812 Methylation IEDB 31844290
Site PTM Type PTM Enzyme Score Source PMID
S51 Phosphorylation HPRD 18691976, 17081983, 18452278, ...19651622, 18669648, 20068231
S53 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S182 Phosphorylation HPRD 18669648, 19664995, 20068231
T449 Phosphorylation HPRD 17322306
S647 Phosphorylation HPRD 19651622, 18691976, 18578522, ...17081983, 20068231
S690 Phosphorylation HPRD 19651622
T693 Phosphorylation HPRD 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S53 T53 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
S116 L116 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S185 T185 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K655 N655 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S672 P672 Biomuta DOID:1324 / lung cancer [ cosmic ]
S678 L678 Biomuta DOID:4159 / skin cancer [ cosmic ]
T693 N693 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K758 E758 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K795 E795 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
C812 Y812 Biomuta DOID:4159 / skin cancer [ cosmic ]