Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9ULR3 / PPM1H_HUMAN
Protein Name Protein phosphatase 1H
Gene Name Name: PPM1H
Organism Homo sapiens (Human)

DAG View
PRO Name protein phosphatase 1H (human)
Definition A protein phosphatase 1H that is encoded in the genome of human.
Short Label hPPM1H
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9ULR3 (PPM1H) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
T111 Phosphorylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus
T113 Phosphorylation HPRD   PhosphoSitePlus 19664995
S118 Phosphorylation PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus
S124 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 23186163, ...20068231
S211 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692
R213 Methylation PhosphoSitePlus
S221 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S223 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T224 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
T227 Phosphorylation PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
K342 Acetylation PhosphoSitePlus
K346 Acetylation PhosphoSitePlus
K346 Ubiquitination PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
Y419 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S422 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S7 Y7 Biomuta DOID:363 / uterine cancer [ tcga ]
T111 S111 Biomuta DOID:2994 / germ cell cancer [ tcga ]
S211 Y211 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
R213 S213 Biomuta DOID:3571 / liver cancer [ icgc ]
T224 M224 Biomuta DOID:1324 / lung cancer [ icgc ]