iPTMnet Report for Q9ULK5 (VANGL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9ULK5 / VANG2_HUMAN
Protein Name Vang-like protein 2
Gene Name Name: VANGL2
Synonyms:KIAA1215,STB1;
Organism Homo sapiens (Human)

PRO ID PR:Q9ULK5
DAG View
PRO Name Vang-like protein 2 (human)
Definition A Vang-like protein 2 that is encoded in the genome of human.
Short Label hVANGL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9ULK5 (VANGL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation PRO   RLIMS-P 25627785
S8 Phosphorylation RLIMS-P 25627785
S11 Phosphorylation RLIMS-P 25627785
S58 Phosphorylation PhosphoSitePlus
S82 Phosphorylation PRO
S84 Phosphorylation PRO
S195 Phosphorylation PhosphoSitePlus
Y196 Phosphorylation PhosphoSitePlus
Y200 Phosphorylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
Y308 Phosphorylation PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
Y341 Phosphorylation PhosphoSitePlus
Y342 Phosphorylation PhosphoSitePlus
Y343 Phosphorylation PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
K507 Ubiquitination PhosphoSitePlus
S517 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T519 Phosphorylation HPRD   PhosphoSitePlus 17081983
S520 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17081983


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049638 (hVANGL2/Phos:1) pS5,pS82,pS84 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S5 F5 Biomuta DOID:4159 / skin cancer [ cosmic ]
S84 P84 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y200 C200 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
S315 I315 Biomuta DOID:363 / uterine cancer [ icgc ]
S520 L520 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]