Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9ULJ3 / ZBT21_HUMAN
Protein Name Zinc finger and BTB domain-containing protein 21
Gene Name Name: ZBTB21
Synonyms:KIAA1227,ZNF295;
Organism Homo sapiens (Human)

PRO ID PR:Q9ULJ3
DAG View
PRO Name zinc finger and BTB domain-containing protein 21 (human)
Definition A zinc finger and BTB domain-containing protein 21 that is encoded in the genome of human.
Short Label hZBTB21
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9ULJ3 (ZBTB21) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K40 Sumoylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
K244 Acetylation PhosphoSitePlus
K273 Acetylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
Y309 Phosphorylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
S332 Phosphorylation PhosphoSitePlus
S343 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S345 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S348 Phosphorylation PhosphoSitePlus
Y353 Phosphorylation PhosphoSitePlus
S354 Phosphorylation PhosphoSitePlus
S361 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S362 Phosphorylation PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus
S370 Phosphorylation PhosphoSitePlus
S381 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332
R398 Methylation PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
S411 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 15302935, 18669648, ...24275569, 19690332
S413 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
T416 Phosphorylation PhosphoSitePlus
S422 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 17525332, 23186163, ...18669648
T425 Phosphorylation phospho.ELM 15302935
K430 Sumoylation PhosphoSitePlus
T431 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...19690332
S434 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
S435 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S438 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S441 Phosphorylation PhosphoSitePlus
T453 Phosphorylation PhosphoSitePlus
S467 Phosphorylation PhosphoSitePlus
K469 Sumoylation PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus
K495 Acetylation PhosphoSitePlus
S504 Phosphorylation PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus
S515 Phosphorylation PhosphoSitePlus
K602 Ubiquitination PhosphoSitePlus
S605 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S608 Phosphorylation PhosphoSitePlus
K617 Sumoylation PhosphoSitePlus
K617 Ubiquitination PhosphoSitePlus
K643 Ubiquitination PhosphoSitePlus
S714 Phosphorylation PhosphoSitePlus   UniProt 23186163, 17081983, 20068231
S739 Phosphorylation PhosphoSitePlus
S759 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K879 Sumoylation PhosphoSitePlus
S972 Phosphorylation PhosphoSitePlus
T979 Phosphorylation PhosphoSitePlus
S981 Phosphorylation PhosphoSitePlus
S983 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S1003 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 18669648, 23186163, ...19690332
T1005 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T1038 Phosphorylation PhosphoSitePlus
K1040 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S343 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S345 Phosphorylation HPRD 18669648, 20068231, 18452278
S348 Phosphorylation HPRD 18077418
S361 Phosphorylation HPRD 17525332
S362 Phosphorylation HPRD 18077418
S381 Phosphorylation HPRD 17525332, 18077418
S411 Phosphorylation HPRD 18669648, 15302935, 19007248
S413 Phosphorylation HPRD 17525332
S422 Phosphorylation HPRD 17525332, 15302935, 18669648, ...19007248
T431 Phosphorylation HPRD 18669648
S434 Phosphorylation HPRD 17322306, 18669648, 20068231
S435 Phosphorylation HPRD 19651622, 18669648, 15302935, ...20068231, 18452278
S438 Phosphorylation HPRD 18669648
S605 Phosphorylation HPRD 18669648, 20068231
S714 Phosphorylation HPRD 19651622, 17081983, 20068231
S759 Phosphorylation HPRD 18669648, 20068231
T979 Phosphorylation HPRD 17081983
S981 Phosphorylation HPRD 17081983
S983 Phosphorylation HPRD 19413330, 15302935
S1003 Phosphorylation HPRD 19413330, 18669648, 15302935, ...20068231, 18452278
T1005 Phosphorylation HPRD 19413330, 19651622, 18669648, ...18452278
Site PTM Type PTM Enzyme Score Source PMID
S343 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S345 Phosphorylation HPRD 18669648, 20068231, 18452278
S348 Phosphorylation HPRD 18077418
S361 Phosphorylation HPRD 17525332
S362 Phosphorylation HPRD 18077418
S381 Phosphorylation HPRD 17525332, 18077418
S411 Phosphorylation HPRD 18669648, 19007248
S413 Phosphorylation HPRD 17525332
S422 Phosphorylation HPRD 17525332, 18669648, 19007248
T431 Phosphorylation HPRD 18669648
S434 Phosphorylation HPRD 17322306, 18669648, 20068231
S435 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S438 Phosphorylation HPRD 18669648
S538 Phosphorylation PhosphoSitePlus
S558 Phosphorylation HPRD 18669648, 20068231
T778 Phosphorylation HPRD 17081983
S780 Phosphorylation HPRD 17081983
S782 Phosphorylation HPRD 19413330
S802 Phosphorylation HPRD 19413330, 18669648, 20068231, ...18452278
T804 Phosphorylation HPRD 19413330, 19651622, 18669648, ...18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S345 L345 Biomuta DOID:1909 / melanoma [ tcga ]
S362 F362 Biomuta DOID:1909 / melanoma [ tcga ]
S365 A365 Biomuta DOID:1909 / melanoma [ cosmic ]
S413 Y413 Biomuta DOID:363 / uterine cancer [ tcga ]
T416 A416 Biomuta DOID:1324 / lung cancer [ tcga ]
T431 N431 Biomuta DOID:3571 / liver cancer [ icgc ]
S434 I434 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ] DOID:8618 / oral cavity cancer [ icgc ]
S441 L441 Biomuta DOID:1324 / lung cancer [ tcga ]
K469 T469 Biomuta DOID:2394 / ovarian cancer [ icgc ]
K495 N495 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K602 E602 Biomuta DOID:363 / uterine cancer [ tcga ]
S739 R739 Biomuta DOID:3571 / liver cancer [ icgc ]
T1005 K1005 Biomuta DOID:3571 / liver cancer [ icgc ]