iPTMnet Report for Q9ULH4 (LRFN2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9ULH4 / LRFN2_HUMAN
Protein Name Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor
Gene Name Name: LRFN2
Synonyms:KIAA1246,SALM1;
Organism Homo sapiens (Human)

PRO ID PR:Q9ULH4
DAG View
PRO Name leucine-rich repeat and fibronectin type-III domain-containing protein 2 (human)
Definition A leucine-rich repeat and fibronectin type-III domain-containing protein 2 that is encoded in the genome of human.
Short Label hLRFN2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9ULH4 (LRFN2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T87 Phosphorylation PhosphoSitePlus
S89 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
T400 Phosphorylation PhosphoSitePlus
S402 Phosphorylation PhosphoSitePlus
S403 O-Glycosylation GlyGen 35254053
S472 Phosphorylation PhosphoSitePlus
S676 Phosphorylation PhosphoSitePlus
T686 Phosphorylation PhosphoSitePlus
Y742 Phosphorylation HPRD   PhosphoSitePlus 19413330
S743 Phosphorylation PhosphoSitePlus
S749 Phosphorylation HPRD   PhosphoSitePlus 19413330
T753 Phosphorylation HPRD   PhosphoSitePlus 19413330
S769 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T87 S87 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S403 R403 Biomuta DOID:3571 / liver cancer [ cosmic ]
T686 M686 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y742 C742 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y742 N742 Biomuta DOID:1324 / lung cancer [ cosmic ]
S749 L749 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T753 M753 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T753 A753 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
S769 I769 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]