Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9ULH0 / KDIS_HUMAN
Protein Name Kinase D-interacting substrate of 220 kDa
Gene Name Name: KIDINS220
Synonyms:ARMS,KIAA1250;
Organism Homo sapiens (Human)

PRO ID PR:Q9ULH0
DAG View
PRO Name kinase D-interacting substrate of 220 kDa (human)
Definition A kinase D-interacting substrate of 220 kDa that is encoded in the genome of human.
Short Label hKIDINS220
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9ULH0 (KIDINS220) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
Y12 Phosphorylation PhosphoSitePlus
K22 Ubiquitination PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
Y169 Phosphorylation PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
Y215 Phosphorylation PhosphoSitePlus
T216 Phosphorylation PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
Y307 Phosphorylation PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
Y398 Phosphorylation PhosphoSitePlus
T406 Phosphorylation PhosphoSitePlus
K416 Ubiquitination PhosphoSitePlus
Y465 Phosphorylation PhosphoSitePlus
K641 Ubiquitination PhosphoSitePlus
K732 Ubiquitination PhosphoSitePlus
K737 Ubiquitination PhosphoSitePlus
K743 Acetylation PhosphoSitePlus
K746 Acetylation PhosphoSitePlus
K746 Ubiquitination PhosphoSitePlus
Y833 Phosphorylation PhosphoSitePlus
K854 Ubiquitination PhosphoSitePlus
S882 Phosphorylation PhosphoSitePlus   UniProt 23186163
S885 Phosphorylation PhosphoSitePlus   UniProt 23186163
K891 Ubiquitination PhosphoSitePlus
S894 Phosphorylation PhosphoSitePlus
K895 Ubiquitination PhosphoSitePlus
T903 Phosphorylation PhosphoSitePlus
T912 Phosphorylation PhosphoSitePlus
T914 Phosphorylation PhosphoSitePlus   UniProt 23186163
S918 Phosphorylation P98161 (PKD1) neXtProt   PhosphoSitePlus   UniProt 18669648, 23186163, 10998417, ...24275569
T927 Phosphorylation PhosphoSitePlus
S932 Phosphorylation PhosphoSitePlus
S947 Phosphorylation PhosphoSitePlus
T949 Phosphorylation PhosphoSitePlus
K1007 Ubiquitination PhosphoSitePlus
K1013 Ubiquitination PhosphoSitePlus
K1057 Ubiquitination PhosphoSitePlus
Y1079 Phosphorylation PhosphoSitePlus
Y1095 Phosphorylation PRO
Y1125 Phosphorylation PhosphoSitePlus
Y1144 Phosphorylation PhosphoSitePlus
Y1146 Phosphorylation PhosphoSitePlus
R1149 Methylation PhosphoSitePlus
Y1150 Phosphorylation PhosphoSitePlus
Y1151 Phosphorylation PhosphoSitePlus
S1155 Phosphorylation PhosphoSitePlus
S1163 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1165 Ubiquitination PhosphoSitePlus
S1167 Phosphorylation PhosphoSitePlus
S1294 Phosphorylation PhosphoSitePlus
S1295 Phosphorylation PhosphoSitePlus
S1296 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1309 Phosphorylation PhosphoSitePlus
Y1324 Phosphorylation PhosphoSitePlus
S1329 Phosphorylation PhosphoSitePlus
S1349 Phosphorylation PhosphoSitePlus
S1352 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1357 Phosphorylation PhosphoSitePlus
S1359 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1361 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1362 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1365 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S1368 Phosphorylation PhosphoSitePlus
S1373 Phosphorylation PhosphoSitePlus
K1378 Ubiquitination PhosphoSitePlus
Y1383 Phosphorylation PhosphoSitePlus
Y1387 Phosphorylation PhosphoSitePlus
Y1390 Phosphorylation PhosphoSitePlus
S1410 Phosphorylation PhosphoSitePlus
S1411 Phosphorylation PhosphoSitePlus
Y1460 Phosphorylation PhosphoSitePlus
S1471 Phosphorylation PhosphoSitePlus
T1477 Phosphorylation PhosphoSitePlus
S1486 Phosphorylation PhosphoSitePlus
S1488 Phosphorylation PhosphoSitePlus
S1521 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S1526 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1528 Phosphorylation PhosphoSitePlus
T1534 Phosphorylation PhosphoSitePlus
S1555 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 20068231
S1559 Phosphorylation PhosphoSitePlus
Y1572 Phosphorylation PhosphoSitePlus
S1574 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1580 Ubiquitination PhosphoSitePlus
S1590 Phosphorylation PhosphoSitePlus
S1594 Phosphorylation PhosphoSitePlus
S1598 Phosphorylation PhosphoSitePlus
S1607 Phosphorylation PhosphoSitePlus
S1621 Phosphorylation PhosphoSitePlus
S1623 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1625 Ubiquitination PhosphoSitePlus
S1631 Phosphorylation PhosphoSitePlus
S1633 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S1661 Phosphorylation PhosphoSitePlus
S1662 Phosphorylation PhosphoSitePlus
Y1674 Phosphorylation PhosphoSitePlus
T1679 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1681 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1682 Phosphorylation PhosphoSitePlus
T1684 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1689 Phosphorylation PhosphoSitePlus
S1709 Phosphorylation PhosphoSitePlus
S1716 Phosphorylation PhosphoSitePlus
S1718 Phosphorylation PhosphoSitePlus
S1731 Phosphorylation PhosphoSitePlus
K1735 Acetylation PhosphoSitePlus
S1737 Phosphorylation PhosphoSitePlus
S1741 Phosphorylation PhosphoSitePlus
S1746 Phosphorylation PhosphoSitePlus
S1757 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S918 Phosphorylation Q15139 (PRKD1) HPRD 18578522, 18669648, 20068231, ...10998417
S1359 Phosphorylation HPRD 18669648
S1361 Phosphorylation HPRD 18669648
S1362 Phosphorylation HPRD 18669648
S1365 Phosphorylation HPRD 18669648
S1521 Phosphorylation HPRD 19413330, 18669648, 20068231
S1526 Phosphorylation HPRD 19413330, 18669648, 20068231
T1528 Phosphorylation HPRD 19413330
S1555 Phosphorylation HPRD 19651622, 18578522, 19691289, ...20068231
S1559 Phosphorylation HPRD 19651622
S1621 Phosphorylation HPRD 20068231
S1716 Phosphorylation HPRD 18669648
S1718 Phosphorylation HPRD 20068231


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048107 (hKIDINS220/Phos:1) pY1095 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K59 N59 Biomuta DOID:363 / uterine cancer [ tcga ]
Y169 C169 Biomuta DOID:5041 / esophageal cancer [ tcga ]
S203 P203 Biomuta DOID:4362 / cervical cancer [ tcga ]
S244 L244 Biomuta DOID:1612 / breast cancer [ icgc ]
S244 * Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
K303 R303 Biomuta DOID:3371 / chondrosarcoma [ cosmic ]
Y398 C398 Biomuta DOID:11934 / head and neck cancer [ icgc, tcga ]
K737 R737 Biomuta DOID:263 / kidney cancer [ cosmic ]
K746 E746 Biomuta DOID:363 / uterine cancer [ tcga ]
Y833 * Biomuta DOID:3571 / liver cancer [ icgc ]
S882 * Biomuta DOID:3571 / liver cancer [ icgc ]
S885 R885 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S918 P918 Biomuta DOID:363 / uterine cancer [ tcga ]
S947 Y947 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
Y1079 C1079 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:2394 / ovarian cancer [ tcga ]
Y1079 N1079 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
Y1125 * Biomuta DOID:3571 / liver cancer [ icgc ]
Y1151 C1151 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y1151 * Biomuta DOID:3571 / liver cancer [ icgc ]
S1167 C1167 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S1309 F1309 Biomuta DOID:1909 / melanoma [ tcga ]
Y1324 * Biomuta DOID:3571 / liver cancer [ icgc ]
Y1324 F1324 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1361 L1361 Biomuta DOID:2531 / hematologic cancer [ icgc ]
S1365 C1365 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1373 * Biomuta DOID:8618 / oral cavity cancer [ icgc ]
S1373 L1373 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
Y1387 C1387 Biomuta DOID:3070 / malignant glioma [ cosmic, icgc, tcga ]
Y1390 * Biomuta DOID:3571 / liver cancer [ icgc ]
Y1460 H1460 Biomuta DOID:363 / uterine cancer [ tcga ]
S1590 Y1590 Biomuta DOID:363 / uterine cancer [ tcga ]
S1594 Y1594 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]