Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9ULG1 / INO80_HUMAN
Protein Name Chromatin-remodeling ATPase INO80
Gene Name Name: INO80
Synonyms:INO80A,INOC1,KIAA1259;
Organism Homo sapiens (Human)

PRO ID PR:Q9ULG1
DAG View
PRO Name chromatin-remodeling ATPase INO80 (human)
Definition A chromatin-remodeling ATPase INO80 that is encoded in the genome of human.
Short Label hINO80
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9ULG1 (INO80) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
S47 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 18452278
S48 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231, 18452278
S51 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231, 18452278
K118 Acetylation PhosphoSitePlus   UniProt 19608861
S140 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
S237 Phosphorylation HPRD 17081983
S240 Phosphorylation PhosphoSitePlus
S255 Phosphorylation PhosphoSitePlus
K264 Acetylation PhosphoSitePlus
K287 Acetylation PhosphoSitePlus
K291 Acetylation PhosphoSitePlus
K294 Acetylation PhosphoSitePlus
S468 Phosphorylation PhosphoSitePlus
K474 Ubiquitination PhosphoSitePlus
K486 Ubiquitination PhosphoSitePlus
S494 Phosphorylation PhosphoSitePlus
K724 Ubiquitination PhosphoSitePlus
K779 Ubiquitination PhosphoSitePlus
S790 Phosphorylation PhosphoSitePlus
K880 Ubiquitination PhosphoSitePlus
T1098 Phosphorylation PhosphoSitePlus
S1100 Phosphorylation PhosphoSitePlus
Y1104 Phosphorylation PhosphoSitePlus
Y1123 Phosphorylation PhosphoSitePlus
S1124 Phosphorylation PhosphoSitePlus
T1127 Phosphorylation PhosphoSitePlus
Y1136 Phosphorylation PhosphoSitePlus
Y1139 Phosphorylation PhosphoSitePlus
S1154 Phosphorylation PhosphoSitePlus
K1217 Ubiquitination PhosphoSitePlus
S1250 Phosphorylation PhosphoSitePlus
T1258 Phosphorylation PhosphoSitePlus
Y1304 Phosphorylation PhosphoSitePlus
R1424 Methylation PhosphoSitePlus
R1429 Methylation PhosphoSitePlus
Y1478 Phosphorylation PhosphoSitePlus
S1487 Phosphorylation PhosphoSitePlus
S1490 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 19691289
S1508 Phosphorylation PhosphoSitePlus
S1511 Phosphorylation PhosphoSitePlus
S1512 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1515 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S1516 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T1550 Phosphorylation HPRD 17693683


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9H981 (ACTR8) S412 Q9ULG1 (INO80) unknown eFIP 29759113


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 L3 Biomuta DOID:363 / uterine cancer [ tcga ]
S240 F240 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
S255 F255 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K264 N264 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S494 R494 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
K880 E880 Biomuta DOID:1909 / melanoma [ cosmic ]
S1508 L1508 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
S1508 * Biomuta DOID:3571 / liver cancer [ icgc ]
S1516 F1516 Biomuta DOID:11934 / head and neck cancer [ tcga ]