iPTMnet Report for Q9ULD2 (MTUS1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9ULD2 / MTUS1_HUMAN
Protein Name Microtubule-associated tumor suppressor 1
Gene Name Name: MTUS1
Synonyms:ATBP,ATIP,GK1,KIAA1288,MTSG1;
Organism Homo sapiens (Human)

PRO ID PR:Q9ULD2
DAG View
PRO Name microtubule-associated tumor suppressor 1 (human)
Definition A mitochondrial tumor suppressor 1 that is encoded in the genome of human.
Short Label hMTUS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9ULD2 (MTUS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
S85 Phosphorylation PhosphoSitePlus
T171 Phosphorylation PhosphoSitePlus
K180 Methylation PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
T186 Phosphorylation PhosphoSitePlus   UniProt 24275569
S197 Phosphorylation PhosphoSitePlus
S279 Phosphorylation PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
S399 Phosphorylation PhosphoSitePlus   UniProt 23186163
S408 Phosphorylation PhosphoSitePlus
T412 Phosphorylation PhosphoSitePlus
T430 Phosphorylation PhosphoSitePlus
S443 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16565220
K462 Ubiquitination PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus
T488 Phosphorylation PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus
S541 Phosphorylation PhosphoSitePlus
T556 Phosphorylation PhosphoSitePlus
T584 Phosphorylation PhosphoSitePlus
T591 Phosphorylation PhosphoSitePlus
S629 Phosphorylation PhosphoSitePlus   UniProt 24275569
T654 Phosphorylation PhosphoSitePlus
Y655 Phosphorylation PhosphoSitePlus
S663 Phosphorylation PhosphoSitePlus
S694 Phosphorylation PhosphoSitePlus
T704 Phosphorylation PhosphoSitePlus
T706 Phosphorylation PhosphoSitePlus
S707 Phosphorylation PhosphoSitePlus
S712 Phosphorylation PhosphoSitePlus
S716 Phosphorylation PhosphoSitePlus
S740 Phosphorylation PhosphoSitePlus
S752 Phosphorylation PhosphoSitePlus
S760 Phosphorylation PhosphoSitePlus
S761 Phosphorylation PhosphoSitePlus
S762 Phosphorylation PhosphoSitePlus
T766 Phosphorylation PhosphoSitePlus
S767 Phosphorylation PhosphoSitePlus
K786 Methylation PhosphoSitePlus
K790 Methylation PhosphoSitePlus
S791 Phosphorylation PhosphoSitePlus
S799 Phosphorylation PhosphoSitePlus
T800 Phosphorylation PhosphoSitePlus
Y825 Phosphorylation PhosphoSitePlus
T858 Phosphorylation PhosphoSitePlus
S878 Phosphorylation PhosphoSitePlus
S916 Phosphorylation PhosphoSitePlus
K955 Ubiquitination PhosphoSitePlus
S958 Phosphorylation PhosphoSitePlus
K1081 Acetylation PhosphoSitePlus
K1082 Ubiquitination PhosphoSitePlus
K1091 Acetylation PhosphoSitePlus
K1091 Ubiquitination PhosphoSitePlus
S1199 Phosphorylation PhosphoSitePlus
S1203 Phosphorylation PhosphoSitePlus
T1204 Phosphorylation PhosphoSitePlus
S1212 Phosphorylation PhosphoSitePlus
S1224 Phosphorylation PhosphoSitePlus   UniProt 20068231
S1241 Phosphorylation PhosphoSitePlus
S1245 Phosphorylation PhosphoSitePlus   UniProt 24275569
T1247 Phosphorylation PhosphoSitePlus
S1255 Phosphorylation PhosphoSitePlus
S1259 Phosphorylation PhosphoSitePlus
S1264 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19690332, 17081983
S1266 Phosphorylation PhosphoSitePlus
S1268 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18669648, ...19690332, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S399 Phosphorylation HPRD 18767875
S443 Phosphorylation HPRD 18767875, 20068231, 16565220
T483 Phosphorylation HPRD 20068231
S528 Phosphorylation HPRD 19413330
S1203 Phosphorylation HPRD 20068231
T1204 Phosphorylation HPRD 20068231
S1224 Phosphorylation HPRD 20068231
S1264 Phosphorylation HPRD 17081983, 20068231
S1266 Phosphorylation HPRD 18767875, 20068231
S1268 Phosphorylation HPRD 18767875, 18669648, 17081983, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
S399 Phosphorylation HPRD 18767875
S443 Phosphorylation HPRD 18767875, 20068231, 16565220
T483 Phosphorylation HPRD 20068231
S528 Phosphorylation HPRD 19413330
S760 Phosphorylation PhosphoSitePlus
S761 Phosphorylation PhosphoSitePlus
S1149 Phosphorylation HPRD   PhosphoSitePlus 20068231
T1150 Phosphorylation HPRD   PhosphoSitePlus 20068231
S1170 Phosphorylation HPRD 20068231
S1210 Phosphorylation HPRD 17081983, 20068231
S1212 Phosphorylation HPRD 18767875, 20068231
S1214 Phosphorylation HPRD 18767875, 18669648, 17081983, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
S8 Phosphorylation PhosphoSitePlus
T11 Phosphorylation PhosphoSitePlus
S369 Phosphorylation HPRD 20068231
T370 Phosphorylation HPRD 20068231
S390 Phosphorylation HPRD 20068231
S430 Phosphorylation HPRD 17081983, 20068231
S432 Phosphorylation HPRD 18767875, 20068231
S434 Phosphorylation HPRD 18767875, 18669648, 17081983, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
T13 Phosphorylation PhosphoSitePlus
T24 Phosphorylation PhosphoSitePlus
S450 Phosphorylation HPRD   PhosphoSitePlus 20068231
T451 Phosphorylation HPRD   PhosphoSitePlus 20068231
S471 Phosphorylation HPRD 20068231
S511 Phosphorylation HPRD 17081983, 20068231
S513 Phosphorylation HPRD 18767875, 20068231
S515 Phosphorylation HPRD 18767875, 18669648, 17081983, ...20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S6 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S183 Y183 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S369 F369 Biomuta DOID:4159 / skin cancer [ cosmic ]
T370 M370 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S390 F390 Biomuta DOID:4159 / skin cancer [ cosmic ]
S408 L408 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S443 L443 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S450 F450 Biomuta DOID:4159 / skin cancer [ cosmic ]
T451 M451 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S471 F471 Biomuta DOID:4159 / skin cancer [ cosmic ]
T483 R483 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T556 A556 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S663 N663 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T704 M704 Biomuta DOID:184 / bone cancer [ cosmic ]
S707 L707 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S740 N740 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S767 F767 Biomuta [ cosmic ]
S791 N791 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S791 R791 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T858 A858 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1081 N1081 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1149 F1149 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1150 M1150 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1170 F1170 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1199 L1199 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S1203 F1203 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1204 M1204 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1212 L1212 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1224 F1224 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1241 R1241 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1245 Y1245 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T1247 S1247 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1259 L1259 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:263 / kidney cancer [ icgc ]