iPTMnet Report for Q9ULC8 (ZDHHC8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9ULC8 / ZDHC8_HUMAN
Protein Name Palmitoyltransferase ZDHHC8
Gene Name Name: ZDHHC8
Synonyms:KIAA1292;
Organism Homo sapiens (Human)

PRO ID PR:Q9ULC8
DAG View
PRO Name palmitoyltransferase ZDHHC8 (human)
Definition A palmitoyltransferase ZDHHC8 that is encoded in the genome of human.
Short Label hZDHHC8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9ULC8 (ZDHHC8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y14 Phosphorylation PhosphoSitePlus
Y91 Phosphorylation PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
S286 Phosphorylation PhosphoSitePlus
K300 Methylation PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
T351 Phosphorylation PhosphoSitePlus
Y405 Phosphorylation PhosphoSitePlus
S417 Phosphorylation PhosphoSitePlus
S434 Phosphorylation PhosphoSitePlus
S438 Phosphorylation phospho.ELM   PhosphoSitePlus 18088087
R441 Methylation PhosphoSitePlus
S453 Phosphorylation PhosphoSitePlus
Y479 Phosphorylation PhosphoSitePlus
S524 Phosphorylation PhosphoSitePlus
S526 Phosphorylation PhosphoSitePlus
S537 Phosphorylation PhosphoSitePlus
Y541 Phosphorylation PhosphoSitePlus
S545 Phosphorylation PhosphoSitePlus
Y579 Phosphorylation PhosphoSitePlus
S606 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
S627 Phosphorylation PhosphoSitePlus
S645 Phosphorylation PhosphoSitePlus
S667 Phosphorylation PhosphoSitePlus
S675 Phosphorylation PhosphoSitePlus   UniProt 23186163
T679 Phosphorylation PhosphoSitePlus
S682 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y685 Phosphorylation PhosphoSitePlus
T716 Phosphorylation PhosphoSitePlus
K720 Methylation PhosphoSitePlus
S725 Phosphorylation PhosphoSitePlus   UniProt 23186163
S741 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S743 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
S754 O-Glycosylation GlyGen 25813380
S754 Phosphorylation PhosphoSitePlus
T759 O-Glycosylation GlyGen 25813380
T759 Phosphorylation PhosphoSitePlus
T760 O-Glycosylation GlyGen 25813380
Y761 Phosphorylation PhosphoSitePlus
S764 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S438 Phosphorylation HPRD 18088087
S526 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y405 C405 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S417 F417 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S526 R526 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y579 C579 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S645 F645 Biomuta DOID:4159 / skin cancer [ cosmic ]
T760 N760 Biomuta DOID:4159 / skin cancer [ cosmic ]