iPTMnet Report for Q9ULC5 (ACSL5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9ULC5 / ACSL5_HUMAN
Protein Name Long-chain-fatty-acid--CoA ligase 5
Gene Name Name: ACSL5
Synonyms:ACS5;ORFNames:UNQ633/PRO1250;
Organism Homo sapiens (Human)

PRO ID PR:Q9ULC5
DAG View
PRO Name long-chain-fatty-acid--CoA ligase 5 (human)
Definition A long-chain-fatty-acid--CoA ligase 5 that is encoded in the genome of human.
Short Label hACSL5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9ULC5 (ACSL5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
I32 Phosphorylation UniProt 18691976
C93 Methylation IEDB 31844290
Y96 Phosphorylation PhosphoSitePlus
S107 O-Glycosylation GlyGen 30397120, 31637018
C121 Methylation IEDB 31844290
Y163 Phosphorylation PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
Y234 Phosphorylation PhosphoSitePlus
K241 Methylation PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
S380 Phosphorylation PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
S408 Phosphorylation PhosphoSitePlus
C494 Methylation IEDB 31844290
K506 Ubiquitination PhosphoSitePlus
T511 Phosphorylation PhosphoSitePlus
Y552 Phosphorylation PhosphoSitePlus
K557 Ubiquitination PhosphoSitePlus
S580 Phosphorylation PhosphoSitePlus
S581 Phosphorylation PhosphoSitePlus
S595 Phosphorylation PhosphoSitePlus
K599 Ubiquitination PhosphoSitePlus
K603 Ubiquitination PhosphoSitePlus
T634 Phosphorylation PhosphoSitePlus
T656 Phosphorylation PhosphoSitePlus
Y678 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S28 Phosphorylation PhosphoSitePlus
S32 Phosphorylation HPRD   PhosphoSitePlus 18691976


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S28 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
Y163 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K344 N344 Biomuta DOID:3571 / liver cancer [ cosmic ]
S380 F380 Biomuta DOID:4159 / skin cancer [ cosmic ]
K404 N404 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ icgc ]
S408 N408 Biomuta DOID:363 / uterine cancer [ icgc ]
K506 N506 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S580 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
S580 L580 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K599 R599 Biomuta DOID:4159 / skin cancer [ cosmic ]