iPTMnet Report for Q9ULB1 (NRXN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9ULB1 / NRX1A_HUMAN
Protein Name Neurexin-1 precursor
Gene Name Name: NRXN1
Synonyms:KIAA0578;
Organism Homo sapiens (Human)

PRO ID PR:Q9ULB1
DAG View
PRO Name neurexin-1-alpha (human)
Definition A neurexin-1-alpha that is encoded in the genome of human.
Short Label hNRXN1-alpha
Category organism-seqgroup

Interactive Sequence View

Select/align proteoforms across species


Q9ULB1 (NRXN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N125 N-Glycosylation GlyGen 29741879
T324 Phosphorylation PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus
S664 Phosphorylation PhosphoSitePlus
T665 Phosphorylation PhosphoSitePlus
S671 Phosphorylation PhosphoSitePlus
S673 Phosphorylation PhosphoSitePlus
R747 Methylation PhosphoSitePlus
T758 Phosphorylation PhosphoSitePlus
S760 Phosphorylation PhosphoSitePlus
T811 Phosphorylation IEDB 35494241
T1002 Phosphorylation IEDB 35494241
S1024 O-Glycosylation GlyGen 30379171
Y1027 Phosphorylation PhosphoSitePlus
T1136 Phosphorylation PhosphoSitePlus
T1340 Phosphorylation PhosphoSitePlus
Y1420 Phosphorylation IEDB 35494241
Y1441 Phosphorylation PhosphoSitePlus
Y1475 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S341 Phosphorylation HPRD 19413330
Site PTM Type PTM Enzyme Score Source PMID
S413 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S341 Y341 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T665 A665 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S673 P673 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R747 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]
R747 Q747 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T811 R811 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1002 I1002 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1024 T1024 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y1420 H1420 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y1420 F1420 Biomuta DOID:3953 / adrenal gland cancer [ tcga ]