iPTMnet Report for Q9UL62 (TRPC5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UL62 / TRPC5_HUMAN
Protein Name Short transient receptor potential channel 5
Gene Name Name: TRPC5
Synonyms:TRP5;
Organism Homo sapiens (Human)

PRO ID PR:Q9UL62
DAG View
PRO Name short transient receptor potential channel 5 (human)
Definition A short transient receptor potential channel 5 that is encoded in the genome of human.
Short Label hTRPC5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UL62 (TRPC5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S205 Phosphorylation PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus
C553 S-Nitrosylation dbSNO 17051229, 22178444, 16998480
C558 S-Nitrosylation dbSNO 17051229, 22178444, 16998480
Y586 Phosphorylation PhosphoSitePlus
Y628 Phosphorylation PhosphoSitePlus
S794 Phosphorylation PhosphoSitePlus
S796 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S205 R205 Biomuta DOID:3571 / liver cancer [ cosmic ]
S207 T207 Biomuta DOID:4159 / skin cancer [ cosmic ]
S490 L490 Biomuta [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc, tcga ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
C553 Y553 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C558 W558 Biomuta DOID:263 / kidney cancer [ cosmic ]
Y628 C628 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]