iPTMnet Report for Q9UL52 (TMPRSS11E)
Protein Information
UniProt AC / UniProt ID | Q9UL52 / TM11E_HUMAN |
Protein Name | Transmembrane protease serine 11E precursor |
Gene Name | Name: TMPRSS11E Synonyms:DESC1,TMPRSS11E2;ORFNames:UNQ742/PRO1461; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UL52 |
PRO Name | transmembrane protease serine 11E (human) |
Definition | A transmembrane protease serine 11E that is encoded in the genome of human. |
Short Label | hTMPRSS11E |
Category | organism-gene |
Q9UL52 (TMPRSS11E) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C35 | Methylation | score1 | IEDB | 31844290 | ||
T60 | Phosphorylation | score1 | PhosphoSitePlus | |||
T61 | Phosphorylation | score1 | PhosphoSitePlus | |||
T168 | Phosphorylation | score1 | PhosphoSitePlus | |||
T250 | Phosphorylation | score1 | PhosphoSitePlus | |||
S254 | Phosphorylation | score1 | PhosphoSitePlus | |||
T353 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T250 | K250 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
T250 | I250 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S254 | L254 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] |