iPTMnet Report for Q9UL12 (SARDH)
Protein Information
| UniProt AC / UniProt ID | Q9UL12 / SARDH_HUMAN |
| Protein Name | Sarcosine dehydrogenase, mitochondrial precursor |
| Gene Name | Name: SARDH Synonyms:DMGDHL1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UL12 |
| PRO Name | sarcosine dehydrogenase, mitochondrial (human) |
| Definition | A sarcosine dehydrogenase, mitochondrial that is encoded in the genome of human. |
| Short Label | hSARDH |
| Category | organism-gene |
Q9UL12 (SARDH) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K166 | Acetylation | score1 | PhosphoSitePlus | |||
| T202 | Phosphorylation | score1 | IEDB | 32387766 | ||
| K578 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K588 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K757 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K775 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y777 | Phosphorylation | score1 | UniProt | 17693683 | ||
| K800 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K802 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T864 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y867 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y869 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K884 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K912 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K588 | N588 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K775 | T775 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| T864 | I864 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K912 | E912 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View