iPTMnet Report for Q9UL01 (DSE)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UL01 / DSE_HUMAN
Protein Name Dermatan-sulfate epimerase precursor
Gene Name Name: DSE
Synonyms:SART2;
Organism Homo sapiens (Human)

PRO ID PR:Q9UL01
DAG View
PRO Name dermatan-sulfate epimerase (human)
Definition A dermatan-sulfate epimerase that is encoded in the genome of human.
Short Label hDSE
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UL01 (DSE) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N183 N-Glycosylation GlyGen   UniProt 19004833
N336 N-Glycosylation GlyGen   UniProt 19004833
S338 O-Glycosylation GlyGen 30379171, 35289036
S338 Phosphorylation PhosphoSitePlus
K421 Acetylation PhosphoSitePlus
K441 Ubiquitination PhosphoSitePlus
K552 Ubiquitination PhosphoSitePlus
Y617 Phosphorylation PhosphoSitePlus
T622 Phosphorylation PhosphoSitePlus
Y624 Phosphorylation PhosphoSitePlus
S625 Phosphorylation PhosphoSitePlus
Y639 Phosphorylation PhosphoSitePlus
Y641 Phosphorylation PhosphoSitePlus
N642 N-Glycosylation GlyGen   UniProt 19004833, 24190977
Y646 Phosphorylation PhosphoSitePlus
N648 N-Glycosylation GlyGen   UniProt 19004833, 24190977
T650 Phosphorylation PhosphoSitePlus
K728 Ubiquitination PhosphoSitePlus
S797 Phosphorylation HPRD   PhosphoSitePlus 18077418
K805 Ubiquitination PhosphoSitePlus
K834 Ubiquitination PhosphoSitePlus
K869 Ubiquitination PhosphoSitePlus
C934 Methylation IEDB 31844290
Y936 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K441 E441 Biomuta DOID:4159 / skin cancer [ cosmic ]
K552 N552 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S625 N625 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y641 C641 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K834 E834 Biomuta [ cosmic ]
K869 N869 Biomuta DOID:363 / uterine cancer [ icgc ]