Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9UKZ1 / CNO11_HUMAN
Protein Name CCR4-NOT transcription complex subunit 11
Gene Name Name: CNOT11
Organism Homo sapiens (Human)

DAG View
PRO Name CCR4-NOT transcription complex subunit 11 (human)
Definition A CCR4-NOT transcription complex subunit 11 that is encoded in the genome of human.
Short Label hCNOT11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9UKZ1 (CNOT11) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation HPRD   PhosphoSitePlus 19415658
S10 Phosphorylation HPRD   PhosphoSitePlus 19415658
R41 Methylation PhosphoSitePlus   UniProt 24129315
R60 Methylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
Y129 Phosphorylation PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K327 Ubiquitination PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
T392 O-Glycosylation GlyGen 29351928
S396 O-Glycosylation GlyGen 29351928
S458 Phosphorylation PhosphoSitePlus
K495 Ubiquitination PhosphoSitePlus
K507 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S106 L106 Biomuta DOID:1612 / breast cancer [ tcga ]
S186 A186 Biomuta DOID:1909 / melanoma [ tcga ]
K319 N319 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K332 N332 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S340 A340 Biomuta DOID:9256 / colorectal cancer [ icgc ]