iPTMnet Report for Q9UKX7 (NUP50)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKX7 / NUP50_HUMAN
Protein Name Nuclear pore complex protein Nup50
Gene Name Name: NUP50
Synonyms:NPAP60L;ORFNames:PRO1146;
Organism Homo sapiens (Human)

PRO ID PR:Q9UKX7
DAG View
PRO Name nuclear pore complex protein Nup50 (human)
Definition A nuclear pore complex protein Nup50 that is encoded in the genome of human.
Short Label hNUP50
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKX7 (NUP50) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K8 Acetylation PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus   UniProt 23186163
K59 Acetylation PhosphoSitePlus
K59 Methylation PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
K62 Methylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
K83 Acetylation PhosphoSitePlus   UniProt 19608861
K83 Ubiquitination PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
K127 Acetylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
C151 Methylation IEDB 31844290
K158 Ubiquitination PhosphoSitePlus
K173 Acetylation PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
C181 S-Nitrosylation dbSNO 26338901
T184 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K192 Acetylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus   UniProt 23186163
K214 Ubiquitination PhosphoSitePlus
T219 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S221 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 21406692, 23186163, 16964243, ...18669648, 19767751, 17287340, 19690332, 20068231, 17081983
S221 Phosphorylation P06493 (CDK1) PhosphoSitePlus   Signor 19767751
S221 Phosphorylation P27361 (MAPK3) PhosphoSitePlus   Signor 19767751
S221 Phosphorylation P28482 (MAPK1) PhosphoSitePlus   Signor 19767751
S223 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
T228 Phosphorylation PhosphoSitePlus
K229 Acetylation PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
T246 Phosphorylation PhosphoSitePlus   UniProt 20068231
K249 Acetylation PhosphoSitePlus
S255 Phosphorylation PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
T259 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 30059200, 21740066, 35254053, 34019948, 31492838, 20305658, 22121020, 34229054
T259 Phosphorylation PhosphoSitePlus   UniProt 20068231
S263 Phosphorylation PhosphoSitePlus
T267 O-Glycosylation GlyGen 31373491
T267 Phosphorylation PhosphoSitePlus
S268 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 32938750, 30059200, 21740066, 35254053, 34019948, 31492838, 20305658, 22121020, 34229054, 29237092
S268 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus   UniProt 23186163
K275 Acetylation PhosphoSitePlus
K275 Methylation PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
S284 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 30059200, 21740066, 35254053, 34019948, 31492838, 20305658, 22121020, 34229054
S284 Phosphorylation PhosphoSitePlus
S287 Phosphorylation PhosphoSitePlus
T291 O-Glycosylation GlyGen 31373491
T291 Phosphorylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus   UniProt 20068231
K305 Ubiquitination PhosphoSitePlus
K311 Acetylation PhosphoSitePlus
S315 Phosphorylation neXtProt   PhosphoSitePlus   Signor 19767751
S315 Phosphorylation P27361 (MAPK3) PhosphoSitePlus   Signor 19767751
S315 Phosphorylation P28482 (MAPK1) PhosphoSitePlus   Signor 19767751
K320 Acetylation PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
S330 Phosphorylation PhosphoSitePlus
K346 Ubiquitination PhosphoSitePlus
K353 Sumoylation PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus
K460 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S141 Phosphorylation HPRD 20068231
S142 Phosphorylation HPRD 20068231
T219 Phosphorylation HPRD 17287340, 20068231
S221 Phosphorylation HPRD 19413330, 17322306, 17287340, ...16964243, 18767875, 19664995, 19651622, 18669648, 20068231
S223 Phosphorylation HPRD 17322306, 19664994, 20068231
T246 Phosphorylation HPRD 20068231
T259 Phosphorylation HPRD 20068231
S263 Phosphorylation HPRD 20068231
S270 Phosphorylation HPRD 20068231
S296 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S113 Phosphorylation HPRD 20068231
S114 Phosphorylation HPRD 20068231
T191 Phosphorylation HPRD 17287340, 20068231
S193 Phosphorylation HPRD 19413330, 17322306, 17287340, ...16964243, 18767875, 19664995, 19651622, 18669648, 20068231
S195 Phosphorylation HPRD 17322306, 19664994, 20068231
T218 Phosphorylation HPRD 20068231
T231 Phosphorylation HPRD 20068231
S235 Phosphorylation HPRD 20068231
S242 Phosphorylation HPRD 20068231
S268 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S74 P74 Biomuta DOID:3571 / liver cancer [ cosmic ]
S115 Y115 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
T184 A184 Biomuta DOID:3571 / liver cancer [ cosmic ]
S208 F208 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K229 Q229 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T231 M231 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T259 M259 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T267 A267 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K275 R275 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
K460 N460 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]