iPTMnet Report for Q9UKX2 (MYH2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKX2 / MYH2_HUMAN
Protein Name Myosin-2
Gene Name Name: MYH2
Synonyms:MYHSA2;
Organism Homo sapiens (Human)

PRO ID PR:Q9UKX2
DAG View
PRO Name myosin-2 (human)
Definition A myosin-2 that is encoded in the genome of human.
Short Label hMYH2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKX2 (MYH2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T51 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
T69 Phosphorylation PhosphoSitePlus
Y163 Phosphorylation PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
Y195 Phosphorylation PhosphoSitePlus
T198 Phosphorylation PhosphoSitePlus
T218 Phosphorylation PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
T258 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
Y269 Phosphorylation PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
T381 Phosphorylation PhosphoSitePlus
Y389 Phosphorylation PhosphoSitePlus
Y404 Phosphorylation PhosphoSitePlus
Y413 Phosphorylation PhosphoSitePlus
T415 Phosphorylation PhosphoSitePlus
K416 Acetylation PhosphoSitePlus
K505 Acetylation PhosphoSitePlus
Y556 Phosphorylation PhosphoSitePlus
T607 Phosphorylation PhosphoSitePlus
Y612 Phosphorylation PhosphoSitePlus
S625 Phosphorylation PhosphoSitePlus
T629 Phosphorylation PhosphoSitePlus
T666 Phosphorylation PhosphoSitePlus
Y721 Phosphorylation PhosphoSitePlus
S734 Phosphorylation PhosphoSitePlus
S744 Phosphorylation PhosphoSitePlus
K746 Acetylation PhosphoSitePlus
S748 Phosphorylation PhosphoSitePlus
T792 Phosphorylation PhosphoSitePlus
Y822 Phosphorylation PhosphoSitePlus
K837 Acetylation PhosphoSitePlus
K847 Acetylation PhosphoSitePlus
K877 Acetylation PhosphoSitePlus
K924 Acetylation PhosphoSitePlus
S954 Phosphorylation PhosphoSitePlus
K957 Acetylation PhosphoSitePlus
K958 Acetylation PhosphoSitePlus
T966 Phosphorylation PhosphoSitePlus
T985 Phosphorylation PhosphoSitePlus
T994 Phosphorylation PhosphoSitePlus
T999 Phosphorylation PhosphoSitePlus
T1025 Phosphorylation PhosphoSitePlus
S1043 Phosphorylation PhosphoSitePlus
K1048 Acetylation PhosphoSitePlus
S1071 Phosphorylation PhosphoSitePlus
S1094 Phosphorylation PhosphoSitePlus
K1112 Acetylation PhosphoSitePlus
R1132 Methylation PhosphoSitePlus
S1134 Phosphorylation PhosphoSitePlus
S1143 Phosphorylation PhosphoSitePlus
S1146 Phosphorylation PhosphoSitePlus
T1163 Phosphorylation PhosphoSitePlus
S1164 Phosphorylation PhosphoSitePlus
T1188 Phosphorylation PhosphoSitePlus
T1194 Phosphorylation PhosphoSitePlus
T1197 Phosphorylation PhosphoSitePlus
S1205 Phosphorylation PhosphoSitePlus
S1228 Phosphorylation PhosphoSitePlus
S1239 Phosphorylation PhosphoSitePlus
T1243 Phosphorylation PhosphoSitePlus
S1245 Phosphorylation PhosphoSitePlus
S1263 Phosphorylation PhosphoSitePlus
S1267 Phosphorylation PhosphoSitePlus
T1280 Phosphorylation PhosphoSitePlus
T1288 Phosphorylation PhosphoSitePlus
S1294 Phosphorylation PhosphoSitePlus
S1305 Phosphorylation PhosphoSitePlus
S1308 Phosphorylation PhosphoSitePlus
T1315 Phosphorylation PhosphoSitePlus
S1341 Phosphorylation PhosphoSitePlus
Y1353 Phosphorylation PhosphoSitePlus
S1359 Phosphorylation PhosphoSitePlus
S1368 Phosphorylation PhosphoSitePlus
T1372 Phosphorylation PhosphoSitePlus
T1379 Phosphorylation PhosphoSitePlus
Y1381 Phosphorylation PhosphoSitePlus
T1383 Phosphorylation PhosphoSitePlus
T1389 Phosphorylation PhosphoSitePlus
K1396 Acetylation PhosphoSitePlus
K1397 Acetylation PhosphoSitePlus
K1398 Acetylation PhosphoSitePlus
T1423 Phosphorylation PhosphoSitePlus
K1450 Acetylation PhosphoSitePlus
S1482 Phosphorylation PhosphoSitePlus
T1485 Phosphorylation PhosphoSitePlus
Y1494 Phosphorylation PhosphoSitePlus
T1503 Phosphorylation PhosphoSitePlus
S1516 Phosphorylation PhosphoSitePlus
T1519 Phosphorylation PhosphoSitePlus
S1576 Phosphorylation PhosphoSitePlus
S1605 Phosphorylation PhosphoSitePlus
T1606 Phosphorylation PhosphoSitePlus
S1613 Phosphorylation PhosphoSitePlus
Y1649 Phosphorylation PhosphoSitePlus
T1652 Phosphorylation PhosphoSitePlus
S1669 Phosphorylation PhosphoSitePlus
S1704 Phosphorylation PhosphoSitePlus
S1716 Phosphorylation PhosphoSitePlus
T1724 Phosphorylation PhosphoSitePlus
T1727 Phosphorylation PhosphoSitePlus
S1728 Phosphorylation PhosphoSitePlus
T1732 Phosphorylation PhosphoSitePlus
K1733 Acetylation PhosphoSitePlus
S1741 Phosphorylation PhosphoSitePlus
T1766 Phosphorylation PhosphoSitePlus
K1776 Acetylation PhosphoSitePlus
K1790 Acetylation PhosphoSitePlus
K1797 Acetylation PhosphoSitePlus
S1834 Phosphorylation PhosphoSitePlus
K1837 Acetylation PhosphoSitePlus
T1857 Phosphorylation PhosphoSitePlus
Y1858 Phosphorylation PhosphoSitePlus
K1865 Acetylation PhosphoSitePlus
S1895 Phosphorylation PhosphoSitePlus
T1897 Phosphorylation PhosphoSitePlus
S1921 Phosphorylation PhosphoSitePlus 11108967
S1921 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 11108967
Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation HPRD 17081983
T1738 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y195 H195 Biomuta DOID:363 / uterine cancer [ icgc ]
Y195 C195 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S263 Y263 Biomuta DOID:363 / uterine cancer [ icgc ]
S263 F263 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K505 T505 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T607 I607 Biomuta DOID:4159 / skin cancer [ cosmic ]
S744 I744 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K924 E924 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K957 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K958 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T985 K985 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T1025 I1025 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1048 N1048 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1071 F1071 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K1112 N1112 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R1132 Q1132 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R1132 W1132 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic, icgc ]
S1143 C1143 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S1143 F1143 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1146 F1146 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1164 L1164 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T1188 A1188 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
T1194 K1194 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1243 M1243 Biomuta DOID:1319 / brain cancer [ cosmic ]
S1263 N1263 Biomuta DOID:1319 / brain cancer [ icgc ]
S1267 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T1280 A1280 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1294 L1294 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S1308 * Biomuta DOID:4606 / bile duct cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
S1308 L1308 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y1353 C1353 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S1359 F1359 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T1379 A1379 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y1381 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y1381 C1381 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T1383 M1383 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1389 R1389 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1423 M1423 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1423 K1423 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1519 M1519 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T1519 K1519 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1605 R1605 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1613 G1613 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1704 I1704 Biomuta DOID:1319 / brain cancer [ icgc ]
S1728 N1728 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1741 F1741 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K1776 M1776 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K1797 N1797 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1834 N1834 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1865 N1865 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]