iPTMnet Report for Q9UKW4 (VAV3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKW4 / VAV3_HUMAN
Protein Name Guanine nucleotide exchange factor VAV3
Gene Name Name: VAV3
Organism Homo sapiens (Human)

PRO ID PR:Q9UKW4
DAG View
PRO Name guanine nucleotide exchange factor VAV3 (human)
Definition A guanine nucleotide exchange factor VAV3 that is encoded in the genome of human.
Short Label hVAV3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKW4 (VAV3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T131 Phosphorylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
Y141 Phosphorylation PhosphoSitePlus   UniProt 19690332
Y160 Phosphorylation PhosphoSitePlus
Y164 Phosphorylation PhosphoSitePlus
Y173 Phosphorylation P12931 (SRC) PRO   PhosphoSitePlus   RLIMS-P   Signor 15708849, 11917103, 17998938
K201 Ubiquitination PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
Y207 Phosphorylation PhosphoSitePlus
T208 Phosphorylation PhosphoSitePlus
T210 Phosphorylation PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
Y217 Phosphorylation PhosphoSitePlus
Y294 Phosphorylation PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus
T298 Phosphorylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
K343 Ubiquitination PhosphoSitePlus
K351 Ubiquitination PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
K414 Ubiquitination PhosphoSitePlus
K435 Ubiquitination PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
K451 Ubiquitination PhosphoSitePlus
Y508 Phosphorylation PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
K528 Ubiquitination PhosphoSitePlus
Y539 Phosphorylation PhosphoSitePlus
S567 Phosphorylation PhosphoSitePlus
T572 Phosphorylation PhosphoSitePlus
K574 Ubiquitination PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
T606 Phosphorylation PhosphoSitePlus
K656 Ubiquitination PhosphoSitePlus
Y667 Phosphorylation PhosphoSitePlus
Y706 Phosphorylation PhosphoSitePlus
K717 Ubiquitination PhosphoSitePlus
K720 Ubiquitination PhosphoSitePlus
K735 Methylation PhosphoSitePlus
K737 Methylation PhosphoSitePlus
S738 Phosphorylation PhosphoSitePlus
K747 Ubiquitination PhosphoSitePlus
S750 Phosphorylation PhosphoSitePlus
K752 Ubiquitination PhosphoSitePlus
K767 Ubiquitination PhosphoSitePlus
S783 Phosphorylation PhosphoSitePlus
S786 Phosphorylation PhosphoSitePlus
K788 Ubiquitination PhosphoSitePlus
Y797 Phosphorylation PhosphoSitePlus
K811 Ubiquitination PhosphoSitePlus
K816 Ubiquitination PhosphoSitePlus
Y818 Phosphorylation PhosphoSitePlus
K820 Ubiquitination PhosphoSitePlus
S840 Phosphorylation PhosphoSitePlus
Y842 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049645 (hVAV3/Phos:1) pY173 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y141 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y173 S173 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K201 N201 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T208 A208 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S213 P213 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S213 L213 Biomuta DOID:4159 / skin cancer [ cosmic ]
T298 S298 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
K311 R311 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y508 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S511 F511 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y667 N667 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K735 I735 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K735 T735 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K747 * Biomuta DOID:3571 / liver cancer [ cosmic ]
K767 N767 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K788 I788 Biomuta [ cosmic ]
S840 Y840 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y842 H842 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]