iPTMnet Report for Q9UKV0 (HDAC9)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKV0 / HDAC9_HUMAN
Protein Name Histone deacetylase 9
Gene Name Name: HDAC9
Synonyms:HDAC7,HDAC7B,HDRP,KIAA0744,MITR;
Organism Homo sapiens (Human)

PRO ID PR:Q9UKV0
DAG View
PRO Name histone deacetylase 9 (human)
Definition A histone deacetylase 9 that is encoded in the genome of human.
Short Label hHDAC9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKV0 (HDAC9) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation PhosphoSitePlus   UniProt 19690332
K44 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
S220 Phosphorylation Q14012 (CAMK1) PhosphoSitePlus 20188095
S239 Phosphorylation Q96GD4 (AURKB) neXtProt   PhosphoSitePlus   Signor 22865920
S240 Phosphorylation PhosphoSitePlus
S253 Phosphorylation Q16512 (PKN1) PhosphoSitePlus 20188095
K409 Ubiquitination PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus
T426 Phosphorylation PhosphoSitePlus
T449 Phosphorylation PhosphoSitePlus
S451 Phosphorylation Q14012 (CAMK1) PhosphoSitePlus 20188095
Site PTM Type PTM Enzyme Score Source PMID
S554 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S220 Phosphorylation PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
Y1007 Phosphorylation HPRD 17081983
Site PTM Type PTM Enzyme Score Source PMID
K97 Ubiquitination PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y1010 Phosphorylation HPRD   phospho.ELM 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K97 N97 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S240 R240 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S240 I240 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S253 L253 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T426 R426 Biomuta DOID:9256 / colorectal cancer [ cosmic ]