iPTMnet Report for Q9UKT9 (IKZF3)
Protein Information
| UniProt AC / UniProt ID | Q9UKT9 / IKZF3_HUMAN |
| Protein Name | Zinc finger protein Aiolos |
| Gene Name | Name: IKZF3 Synonyms:ZNFN1A3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UKT9 |
| PRO Name | zinc finger protein Aiolos (human) |
| Definition | A zinc finger protein Aiolos that is encoded in the genome of human. |
| Short Label | hIKZF3 |
| Category | organism-gene |
DAG ViewQ9UKT9 (IKZF3) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S57 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S65 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K73 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S74 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S90 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y96 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K100 | Sumoylation | score1 | PhosphoSitePlus | |||
| K100 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S115 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T141 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K158 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T169 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| K172 | Sumoylation | score1 | PhosphoSitePlus | |||
| K200 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K203 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K221 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K245 | Acetylation | score1 | PhosphoSitePlus | |||
| K245 | Sumoylation | score1 | PhosphoSitePlus | |||
| K245 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S261 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K265 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K273 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C281 | Methylation | score1 | IEDB | 31844290 | ||
| Y286 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y290 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T326 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S352 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K361 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K362 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K369 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S378 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K419 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K429 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K444 | Ubiquitination | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S139 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T141 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y146 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T169 | Phosphorylation | score0 | HPRD | 18669648 | ||
| K239 | Ubiquitination | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T141 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S57 | L57 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S65 | N65 | Biomuta | DOID:5041 / esophageal cancer [ cosmic, icgc ] | |
| S65 | R65 | Biomuta | DOID:5041 / esophageal cancer [ cosmic, icgc ] | |
| S90 | L90 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] [ cosmic ] | |
| S115 | N115 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| T141 | A141 | Biomuta | [ cosmic ] | |
| K158 | T158 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K172 | N172 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ] | |
| K273 | R273 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K444 | E444 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] |
