iPTMnet Report for Q9UKT4 (FBXO5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKT4 / FBX5_HUMAN
Protein Name F-box only protein 5
Gene Name Name: FBXO5
Synonyms:EMI1;
Organism Homo sapiens (Human)

PRO ID PR:Q9UKT4
DAG View
PRO Name F-box only protein 5 (human)
Definition An F-box only protein 5 that is encoded in the genome of human.
Short Label hFBXO5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKT4 (FBXO5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
K64 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
Y90 Phosphorylation PhosphoSitePlus
S98 Phosphorylation PhosphoSitePlus
S102 Phosphorylation IEDB   PhosphoSitePlus   UniProt 35494241, 23186163
Y142 Phosphorylation P12931 (SRC) PhosphoSitePlus   RLIMS-P   Signor 20717963
S145 Phosphorylation P53350 (PLK1) neXtProt   PRO   PhosphoSitePlus 15469984, 15148369
S149 Phosphorylation P53350 (PLK1) neXtProt   PRO   PhosphoSitePlus 15469984, 15148369
S182 Phosphorylation PRO
K238 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
Y318 Phosphorylation PhosphoSitePlus
T323 Phosphorylation IEDB   PhosphoSitePlus 32387766
S331 Phosphorylation PhosphoSitePlus
T335 Phosphorylation PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
K352 Sumoylation PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
Y356 Phosphorylation PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
Y387 Phosphorylation PhosphoSitePlus
T437 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S16 Phosphorylation HPRD 20068231
S20 Phosphorylation HPRD 20068231
S22 Phosphorylation HPRD 20068231


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047378 (hFBXO5/Phos:1) pS145,pS149 PRO
PR:000047379 (hFBXO5/Phos:2) pS182 PRO
PR:000047380 (hFBXO5/PhosRes+) p PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S98 L98 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S182 T182 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T323 N323 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S346 F346 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]