iPTMnet Report for Q9UKL0 (RCOR1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKL0 / RCOR1_HUMAN
Protein Name REST corepressor 1
Gene Name Name: RCOR1
Synonyms:KIAA0071,RCOR;
Organism Homo sapiens (Human)

PRO ID PR:Q9UKL0
DAG View
PRO Name REST corepressor 1 (human)
Definition A REST corepressor 1 that is encoded in the genome of human.
Short Label hRCOR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKL0 (RCOR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
S127 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
S139 Phosphorylation PhosphoSitePlus
Y152 Phosphorylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
T189 Phosphorylation PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...19690332, 20068231
T290 O-Glycosylation GlyGen 23301498, 34019948, 28510447, ...33465208
T292 O-Glycosylation GlyGen 33465208
K297 Sumoylation PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
K365 Ubiquitination PhosphoSitePlus
Y373 Phosphorylation PhosphoSitePlus
K381 Ubiquitination PhosphoSitePlus
K421 Acetylation PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
T449 Phosphorylation PhosphoSitePlus
S453 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S464 Phosphorylation PhosphoSitePlus
K466 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S94 L94 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S235 Y235 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:11054 / urinary bladder cancer [ cosmic ]
S360 G360 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K365 N365 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S453 C453 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S464 F464 Biomuta DOID:10534 / stomach cancer [ cosmic ]