Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKJ3 / GPTC8_HUMAN
Protein Name G patch domain-containing protein 8
Gene Name Name: GPATCH8
Synonyms:GPATC8,KIAA0553;
Organism Homo sapiens (Human)

PRO ID PR:Q9UKJ3
DAG View
PRO Name G patch domain-containing protein 8 (human)
Definition A G patch domain-containing protein 8 that is encoded in the genome of human.
Short Label hGPATCH8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKJ3 (GPATCH8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K50 Ubiquitination PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
Y76 Phosphorylation PhosphoSitePlus
Y118 Phosphorylation PhosphoSitePlus
Y137 Phosphorylation PhosphoSitePlus
K188 Methylation PhosphoSitePlus
T293 Phosphorylation PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
K311 Acetylation PhosphoSitePlus
T327 Phosphorylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus
Y394 Phosphorylation PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
K456 Acetylation PhosphoSitePlus
T457 Phosphorylation PhosphoSitePlus
S459 Phosphorylation PhosphoSitePlus
S469 Phosphorylation PhosphoSitePlus
S491 Phosphorylation PhosphoSitePlus   UniProt 23186163
S499 Phosphorylation PhosphoSitePlus
S510 Phosphorylation PhosphoSitePlus
S517 Phosphorylation PhosphoSitePlus
T520 Phosphorylation PhosphoSitePlus
S526 Phosphorylation PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
Y573 Phosphorylation PhosphoSitePlus
S635 Phosphorylation PhosphoSitePlus
S637 Phosphorylation PhosphoSitePlus
S640 Phosphorylation PhosphoSitePlus
S650 Phosphorylation PhosphoSitePlus
S653 Phosphorylation PhosphoSitePlus   UniProt 23186163
T655 Phosphorylation PhosphoSitePlus
S738 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S740 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 24275569
S758 Phosphorylation PhosphoSitePlus   UniProt 18669648
S766 Phosphorylation PhosphoSitePlus
S815 Phosphorylation PhosphoSitePlus
S832 Phosphorylation PhosphoSitePlus
S837 Phosphorylation PhosphoSitePlus
S845 Phosphorylation PhosphoSitePlus
S847 Phosphorylation PhosphoSitePlus
S861 Phosphorylation PhosphoSitePlus
S862 Phosphorylation PhosphoSitePlus
S871 Phosphorylation PhosphoSitePlus
S874 Phosphorylation PhosphoSitePlus
S878 Phosphorylation PhosphoSitePlus
C882 S-Nitrosylation dbSNO 26338901
Y889 Phosphorylation PhosphoSitePlus
S893 Phosphorylation PhosphoSitePlus
Y894 Phosphorylation PhosphoSitePlus
S898 Phosphorylation PhosphoSitePlus
S908 Phosphorylation PhosphoSitePlus
S911 Phosphorylation PhosphoSitePlus
S914 Phosphorylation PhosphoSitePlus
Y916 Phosphorylation PhosphoSitePlus
S918 Phosphorylation PhosphoSitePlus
S923 Phosphorylation PhosphoSitePlus
S931 Phosphorylation PhosphoSitePlus
S940 Phosphorylation PhosphoSitePlus
S942 Phosphorylation PhosphoSitePlus
S944 Phosphorylation PhosphoSitePlus
S954 Phosphorylation PhosphoSitePlus
S960 Phosphorylation PhosphoSitePlus
S974 Phosphorylation PhosphoSitePlus
S976 Phosphorylation PhosphoSitePlus
T977 Phosphorylation PhosphoSitePlus
T978 Phosphorylation PhosphoSitePlus
S981 Phosphorylation PhosphoSitePlus   UniProt 21406692
S985 Phosphorylation PhosphoSitePlus
S987 Phosphorylation PhosphoSitePlus
S1009 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1014 Phosphorylation PhosphoSitePlus   UniProt 23186163, 17081983
Y1031 Phosphorylation PhosphoSitePlus
S1033 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S1035 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 21406692
Y1038 Phosphorylation PhosphoSitePlus
S1058 Phosphorylation PhosphoSitePlus
S1065 Phosphorylation PhosphoSitePlus
S1068 Phosphorylation PhosphoSitePlus
T1072 Phosphorylation PhosphoSitePlus
S1076 Phosphorylation PhosphoSitePlus
S1081 Phosphorylation PhosphoSitePlus   UniProt 18669648
K1096 Acetylation PhosphoSitePlus
S1107 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...19690332, 20068231
S1109 Phosphorylation PhosphoSitePlus
T1115 Phosphorylation PhosphoSitePlus
Y1130 Phosphorylation PhosphoSitePlus
K1142 Acetylation PhosphoSitePlus
K1150 Acetylation PhosphoSitePlus
S1260 Phosphorylation PhosphoSitePlus
K1322 Acetylation PhosphoSitePlus
K1322 Ubiquitination PhosphoSitePlus
K1338 Ubiquitination PhosphoSitePlus
K1341 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T293 Phosphorylation HPRD 18669648
T373 Phosphorylation HPRD 20068231
Y394 Phosphorylation HPRD 17287340
S499 Phosphorylation HPRD 17525332
S503 Phosphorylation HPRD 20068231
T505 Phosphorylation HPRD 20068231
S650 Phosphorylation HPRD 15302935
S653 Phosphorylation HPRD 19413330, 17081983, 20068231
T655 Phosphorylation HPRD 19651622, 15302935
S738 Phosphorylation HPRD 18669648, 19664995, 20068231
S740 Phosphorylation HPRD 19651622, 18767875, 18669648, ...19664995, 20068231
S758 Phosphorylation HPRD 18669648, 19007248
S804 Phosphorylation HPRD 20068231
S807 Phosphorylation HPRD 20068231
S908 Phosphorylation HPRD 19651622
S911 Phosphorylation HPRD 19651622
S914 Phosphorylation HPRD 19651622
S956 Phosphorylation HPRD 20068231
S960 Phosphorylation HPRD 20068231
S974 Phosphorylation HPRD 19651622
S976 Phosphorylation HPRD 19651622, 20068231
T977 Phosphorylation HPRD 19651622
T978 Phosphorylation HPRD 19651622
S981 Phosphorylation HPRD 19651622
S1009 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18452278
S1014 Phosphorylation HPRD 17322306, 19651622, 20068231
Y1031 Phosphorylation HPRD 17081983
S1033 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 18707149
S1035 Phosphorylation HPRD 18767875, 19664995, 16565220, ...19651622, 18669648, 18707149, 20068231
T1072 Phosphorylation HPRD 18669648
S1076 Phosphorylation HPRD 19413330, 18669648
S1081 Phosphorylation HPRD 19413330, 18669648
S1107 Phosphorylation HPRD 19413330, 17081983, 18767875, ...18452278, 19651622, 18669648, 20068231
S1109 Phosphorylation HPRD 19413330, 18669648
T1115 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y76 * Biomuta DOID:363 / uterine cancer [ tcga ]
Y76 C76 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S303 A303 Biomuta DOID:1909 / melanoma [ tcga ]
S499 N499 Biomuta DOID:1324 / lung cancer [ tcga ]
T505 A505 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S650 R650 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:263 / kidney cancer [ cosmic ]
S807 A807 Biomuta DOID:3571 / liver cancer [ icgc ]
S847 I847 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S861 F861 Biomuta DOID:1909 / melanoma [ tcga ]
S871 L871 Biomuta DOID:263 / kidney cancer [ cosmic ]
S923 L923 Biomuta DOID:5041 / esophageal cancer [ icgc ]
S940 R940 Biomuta DOID:3571 / liver cancer [ icgc ]
S944 R944 Biomuta DOID:3571 / liver cancer [ icgc ]
S956 F956 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S987 R987 Biomuta DOID:3571 / liver cancer [ icgc ]
S1033 P1033 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
S1260 R1260 Biomuta DOID:8618 / oral cavity cancer [ icgc ]