iPTMnet Report for Q9UKI8 (TLK1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKI8 / TLK1_HUMAN
Protein Name Serine/threonine-protein kinase tousled-like 1
Gene Name Name: TLK1
Synonyms:KIAA0137;
Organism Homo sapiens (Human)

PRO ID PR:Q9UKI8
DAG View
PRO Name serine/threonine-protein kinase tousled-like 1 (human)
Definition A serine/threonine-protein kinase tousled-like 1 that is encoded in the genome of human.
Short Label hTLK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKI8 (TLK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S22 Phosphorylation PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
T38 Phosphorylation PhosphoSitePlus   UniProt 23186163
S41 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus   UniProt 23186163
T68 Phosphorylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus   UniProt 23186163
T78 Phosphorylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus
T89 Phosphorylation PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
S159 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 23186163, 19690332, ...20068231
S170 Phosphorylation PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus
S188 Phosphorylation IEDB   PhosphoSitePlus 33936100
S190 Phosphorylation IEDB 31848261
T192 Phosphorylation PhosphoSitePlus
K234 Acetylation PhosphoSitePlus
T304 Phosphorylation PhosphoSitePlus
T313 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus
K485 Ubiquitination PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
Y524 Phosphorylation IEDB 35494241
S563 Phosphorylation PhosphoSitePlus
S611 Phosphorylation PhosphoSitePlus
S679 Phosphorylation PhosphoSitePlus
T688 Phosphorylation PhosphoSitePlus
K700 Ubiquitination PhosphoSitePlus
S741 Phosphorylation PhosphoSitePlus
S743 Phosphorylation O14757 (CHEK1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 20581459, 12660173
S744 Phosphorylation PhosphoSitePlus
S760 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S158 Phosphorylation HPRD 20068231
S159 Phosphorylation HPRD 18767875, 19664994, 19664995, ...20068231, 18452278
T179 Phosphorylation HPRD 17081983
S190 Phosphorylation HPRD 17081983
S741 Phosphorylation HPRD 18669648, 20068231
S743 Phosphorylation O14757 (CHEK1) HPRD 12955071, 18669648, 12660173, ...20068231
S744 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S700 Phosphorylation O14757 (CHEK1) PhosphoSitePlus 21851590
S764 Phosphorylation O14757 (CHEK1) PhosphoSitePlus 12660173
S783 Phosphorylation phospho.ELM 18669648
Site PTM Type PTM Enzyme Score Source PMID
S37 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus


Q9UKI8 (TLK1) as PTM Enzyme



Substrate Site Score Source PMID
Q99638 (RAD9A) S328 phospho.ELM   PhosphoSitePlus   Signor 24376897, 18940270
Q99638 (RAD9A) T355 PhosphoSitePlus   Signor 24376897