iPTMnet Report for Q9UKI2 (CDC42EP3)
Protein Information
| UniProt AC / UniProt ID | Q9UKI2 / BORG2_HUMAN |
| Protein Name | Cdc42 effector protein 3 |
| Gene Name | Name: CDC42EP3 Synonyms:BORG2,CEP3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UKI2 |
| PRO Name | Cdc42 effector protein 3 (human) |
| Definition | A Cdc42 effector protein 3 that is encoded in the genome of human. |
| Short Label | hCDC42EP3 |
| Category | organism-gene |
DAG ViewQ9UKI2 (CDC42EP3) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Phosphorylation | score1 | PRO | ||||
| Y8 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K10 | Methylation | score1 | PhosphoSitePlus | |||
| K15 | Methylation | score1 | PhosphoSitePlus | |||
| S27 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S32 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y63 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S89 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 23186163, 17081983, 18212344 | ||
| T90 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S91 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 15345747 | ||
| S93 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T98 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S100 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 17081983, 18212344 | ||
| S108 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S124 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S144 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S157 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T164 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T218 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S220 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000046663 (hCDC42EP3/PhosRes+) | p | PRO |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S32 | R32 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T90 | P90 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| S91 | L91 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
| S93 | Y93 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| T98 | M98 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S220 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] |
