iPTMnet Report for Q9UKG9 (CROT)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKG9 / OCTC_HUMAN
Protein Name Peroxisomal carnitine O-octanoyltransferase
Gene Name Name: CROT
Synonyms:COT;
Organism Homo sapiens (Human)

PRO ID PR:Q9UKG9
DAG View
PRO Name peroxisomal carnitine O-octanoyltransferase (human)
Definition A peroxisomal carnitine O-octanoyltransferase that is encoded in the genome of human.
Short Label hCROT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKG9 (CROT) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
Y35 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
K358 Acetylation PhosphoSitePlus
Y387 Phosphorylation PhosphoSitePlus
T409 Phosphorylation PhosphoSitePlus
Y428 Phosphorylation PhosphoSitePlus
Y429 Phosphorylation PhosphoSitePlus
C458 Methylation IEDB 31844290
S533 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y35 S35 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S38 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K57 N57 Biomuta DOID:9256 / colorectal cancer [ icgc ]