iPTMnet Report for Q9UKD1 (GMEB2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKD1 / GMEB2_HUMAN
Protein Name Glucocorticoid modulatory element-binding protein 2
Gene Name Name: GMEB2
Synonyms:KIAA1269;
Organism Homo sapiens (Human)

PRO ID PR:Q9UKD1
DAG View
PRO Name glucocorticoid modulatory element-binding protein 2 (human)
Definition A glucocorticoid modulatory element-binding protein 2 that is encoded in the genome of human.
Short Label hGMEB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKD1 (GMEB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation HPRD 20068231
S26 Phosphorylation HPRD 20068231
K107 Ubiquitination PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
S126 Phosphorylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
K155 Sumoylation PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
K179 Sumoylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
T348 Phosphorylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
T365 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus   UniProt 19690332
S403 O-Glycosylation GlyGen 34846842, 20068230, 30379171, ...32574038, 34019948, 28657654, 35254053, 35289036, 35132862, 30620550, 31492838, 31373491, 36240223, 29351928, 22661428, 29237092, 30059200
T404 O-Glycosylation GlyGen   PhosphoSitePlus 34846842, 20068230, 30379171, ...32574038, 34019948, 28657654, 35254053, 35289036, 35132862, 30620550, 31492838, 36240223, 29351928, 22661428, 29237092, 30059200
S407 O-Glycosylation GlyGen 34846842, 20068230, 30379171, ...32574038, 34019948, 28657654, 35254053, 35289036, 35132862, 30620550, 31492838, 36240223, 29351928, 22661428, 29237092, 30059200
T408 O-Glycosylation GlyGen 34846842, 20068230, 30379171, ...32574038, 34019948, 28657654, 35254053, 35289036, 35132862, 30620550, 31492838, 36240223, 29351928, 22661428, 29237092, 30059200
S414 O-Glycosylation GlyGen 34846842, 20068230, 30379171, ...32574038, 34019948, 28657654, 35254053, 35289036, 35132862, 30620550, 31492838, 36240223, 29351928, 22661428, 29237092, 30059200
S421 O-Glycosylation GlyGen 34846842, 20068230, 30379171, ...32574038, 34019948, 28657654, 35254053, 35289036, 35132862, 30620550, 31492838, 36240223, 29351928, 22661428, 29237092, 30059200
S422 O-Glycosylation GlyGen 34846842, 20068230, 30379171, ...32574038, 34019948, 28657654, 35254053, 35289036, 35132862, 30620550, 31492838, 36240223, 29351928, 22661428, 29237092, 30059200
S425 O-Glycosylation GlyGen 34846842, 20068230, 30379171, ...32574038, 34019948, 28657654, 35254053, 35289036, 35132862, 30620550, 31492838, 36240223, 29351928, 22661428, 29237092, 30059200
T432 O-Glycosylation GlyGen 34846842, 20068230, 30379171, ...32574038, 34019948, 28657654, 35254053, 35289036, 35132862, 30620550, 31492838, 36240223, 29351928, 22661428, 29237092, 30059200
S436 O-Glycosylation GlyGen 34846842, 20068230, 30379171, ...32574038, 34019948, 28657654, 35254053, 35289036, 35132862, 30620550, 31492838, 36240223, 29351928, 22661428, 29237092, 30059200
S437 O-Glycosylation GlyGen 34846842, 20068230, 30379171, ...32574038, 34019948, 28657654, 35254053, 35289036, 35132862, 30620550, 31492838, 36240223, 29351928, 22661428, 29237092, 30059200
S443 O-Glycosylation GlyGen 34846842, 20068230, 30379171, ...32574038, 34019948, 28657654, 35254053, 35289036, 35132862, 30620550, 31492838, 36240223, 29351928, 22661428, 29237092, 30059200
T444 O-Glycosylation GlyGen 34846842, 20068230, 30379171, ...32574038, 34019948, 28657654, 35254053, 35289036, 35132862, 30620550, 31492838, 36240223, 29351928, 22661428, 29237092, 30059200
S453 O-Glycosylation GlyGen 34846842, 20068230, 30379171, ...32574038, 34019948, 28657654, 35254053, 35289036, 35132862, 30620550, 31492838, 36240223, 29351928, 22661428, 29237092, 30059200
T455 O-Glycosylation GlyGen 34846842, 20068230, 30379171, ...32574038, 34019948, 28657654, 35254053, 35289036, 35132862, 30620550, 31492838, 36240223, 29351928, 22661428, 29237092, 30059200


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S421 G421 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S437 F437 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T455 M455 Biomuta DOID:263 / kidney cancer [ cosmic ]