Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKC9 / FBXL2_HUMAN
Protein Name F-box/LRR-repeat protein 2
Gene Name Name: FBXL2
Synonyms:FBL2;
Organism Homo sapiens (Human)

PRO ID PR:Q9UKC9
DAG View
PRO Name F-box/LRR-repeat protein 2 (human)
Definition An F-box/LRR-repeat protein 2 that is encoded in the genome of human.
Short Label hFBXL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKC9 (FBXL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
K13 Ubiquitination PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
T404 Phosphorylation PhosphoSitePlus   RLIMS-P 27010866, 23542741


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O00459 (PIK3R2) Y655 Q9UKC9 (FBXL2) inhibited_association eFIP 23604317


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K13 E13 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]