iPTMnet Report for Q9UKB1 (FBXW11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKB1 / FBW1B_HUMAN
Protein Name F-box/WD repeat-containing protein 11
Gene Name Name: FBXW11
Synonyms:BTRCP2;
Organism Homo sapiens (Human)

PRO ID PR:Q9UKB1
DAG View
PRO Name F-box/WD repeat-containing protein 11 (human)
Definition An F-box/WD repeat-containing protein 11 that is encoded in the genome of human.
Short Label hFBXW11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKB1 (FBXW11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S65 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
K179 Methylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
C235 Methylation IEDB 31844290
K241 Ubiquitination PhosphoSitePlus
C245 Methylation IEDB 31844290
K252 Ubiquitination PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
C393 Methylation IEDB 31844290
K464 Ubiquitination PhosphoSitePlus
S534 Phosphorylation PhosphoSitePlus
T536 Phosphorylation PhosphoSitePlus
Y537 Phosphorylation PhosphoSitePlus
T538 Phosphorylation PhosphoSitePlus
Y539 Phosphorylation PhosphoSitePlus
S541 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S18 Phosphorylation PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9Y2X9 (ZNF281) S638 Q9UKB1 (FBXW11) unknown eFIP 29179460


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000035772 (hCTNNB1/iso:1/Phos:3) NOT Interaction PR:Q9UKB1 (hFBXW11) PRO 10074433


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S28 F28 Biomuta DOID:4159 / skin cancer [ cosmic ]
K267 T267 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S541 C541 Biomuta DOID:4606 / bile duct cancer [ cosmic ]